The finding means that barriers to treating the disease, such as resistance to the drug temozolomide, may be overcome. The study, by Forsyth and colleagues in Canada, Texas and Florida, appeared in a recent issue ofNeuro-Oncology.
“Although temozolomide improves survival for patients with glioblastoma multiforme, drug resistance is a significant obstacle,” said Forsyth, the study lead author. “Oncolytic viruses that infect and break down cancer cellsoffer promising possibilities for overcoming resistance to targeted therapies.”
The authors note that oncolytic viruses have the potential to provoke a multipronged attack…
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