part 1………http://orgspectroscopyint.blogspot.in/2015/04/venlafaxine.html / https://newdrugapprovals.org/2015/04/09/venlafaxine-part-12/
part 2……..https://newdrugapprovals.org/2015/04/09/venlafaxine-22/
PART 3…..http://orgspectroscopyint.blogspot.in/2015/04/venlafaxine-part-33.html
SEE ALSO
http://www.google.com/patents/WO2008059525A2?cl=en
WILL BE UPDATED………..
Chemistry
Systematic (IUPAC) name | |
---|---|
(RS)-1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]cyclohexanol | |
Clinical data | |
Trade names | Effexor XR, Effexor, Trevilor |
AHFS/Drugs.com | monograph |
Licence data | US Daily Med:link |
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Oral | |
Pharmacokinetic data | |
Bioavailability | 42±15%[1] |
Protein binding | 27±2% (parent compound), 30±12% (active metabolite,desvenlafaxine)[2] |
Metabolism | Hepatic (~50% of the parent compound is metabolised on first pass through the liver)[1][2] |
Half-life | 5±2 h (parent compound for immediate release preparations), 15±6 h (parent compound for extended release preparations), 11±2 h (active metabolite)[1][2] |
Excretion | Renal (87%; 5% as unchanged drug; 29% asdesvenlafaxine and 53% as other metabolites)[1][2] |
Identifiers | |
93413-69-5 | |
N06AX16 | |
PubChem | CID 5656 |
DrugBank | DB00285 |
ChemSpider | 5454 |
UNII | GRZ5RCB1QG |
ChEBI | CHEBI:9943 |
ChEMBL | CHEMBL637 |
Chemical data | |
Formula | C17H27NO2 |
277.402 g/mol |
HSQC
1H NMR PREDICT OF HCL
13C NMR PREDICT OF HCL
BASE
External links[Drug information
- U.S. Food and Drug Administration information on Effexor
- Efexor patient information leaflet (UK)
- Effexor XR prescribing information for healthcare professionals (pdf) (USA only) Archived from the original on 17 September 2006.
- Detailed Patient/Parent Information on Effexor
- List of international brand names for Venlafaxine
- U.S. National Library of Medicine: Drug Information Portal -Venlafaxine
Diagnostic tools
Patient experiences
: The views expressed are my personal and in no-way suggest the views
of the professional body or the company that I represent.
: The views expressed are my personal and in no-way suggest the views
of the professional body or the company that I represent.
: The views expressed are my personal and in no-way suggest the views
of the professional body or the company that I represent.
COCK SAYS MOM CAN TEACH YOU NMR
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