New Drug Approvals
Follow New Drug Approvals on WordPress.com

FLAGS AND HITS

Flag Counter
DRUG APPROVALS BY DR ANTHONY MELVIN CRASTO

Archives

Categories

Join me on Linkedin

View Anthony Melvin Crasto Ph.D's profile on LinkedIn

Join me on Researchgate

Anthony Melvin Crasto Dr.

  Join me on Facebook FACEBOOK   ...................................................................Join me on twitter Follow amcrasto on Twitter     ..................................................................Join me on google plus Googleplus

MYSELF

DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 36Yrs Exp. in the feld of Organic Chemistry,Working for AFRICURE PHARMA as ADVISOR earlier with GLENMARK PHARMA at Navi Mumbai, INDIA. Serving chemists around the world. Helping them with websites on Chemistry.Million hits on google, NO ADVERTISEMENTS , ACADEMIC , NON COMMERCIAL SITE, world acclamation from industry, academia, drug authorities for websites, blogs and educational contribution, ........amcrasto@gmail.com..........+91 9323115463, Skype amcrasto64 View Anthony Melvin Crasto Ph.D's profile on LinkedIn Anthony Melvin Crasto Dr.

Enter your email address to follow this blog and receive notifications of new posts by email.

Join 37.8K other subscribers
DR ANTHONY MELVIN CRASTO Ph.D

DR ANTHONY MELVIN CRASTO Ph.D

DR ANTHONY MELVIN CRASTO, Born in Mumbai in 1964 and graduated from Mumbai University, Completed his Ph.D from ICT, 1991,Matunga, Mumbai, India, in Organic Chemistry, The thesis topic was Synthesis of Novel Pyrethroid Analogues, Currently he is working with AFRICURE PHARMA, ROW2TECH, NIPER-G, Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Govt. of India as ADVISOR, earlier assignment was with GLENMARK LIFE SCIENCES LTD, as CONSUlTANT, Retired from GLENMARK in Jan2022 Research Centre as Principal Scientist, Process Research (bulk actives) at Mahape, Navi Mumbai, India. Total Industry exp 32 plus yrs, Prior to joining Glenmark, he has worked with major multinationals like Hoechst Marion Roussel, now Sanofi, Searle India Ltd, now RPG lifesciences, etc. He has worked with notable scientists like Dr K Nagarajan, Dr Ralph Stapel, Prof S Seshadri, etc, He did custom synthesis for major multinationals in his career like BASF, Novartis, Sanofi, etc., He has worked in Discovery, Natural products, Bulk drugs, Generics, Intermediates, Fine chemicals, Neutraceuticals, GMP, Scaleups, etc, he is now helping millions, has 9 million plus hits on Google on all Organic chemistry websites. His friends call him Open superstar worlddrugtracker. His New Drug Approvals, Green Chemistry International, All about drugs, Eurekamoments, Organic spectroscopy international, etc in organic chemistry are some most read blogs He has hands on experience in initiation and developing novel routes for drug molecules and implementation them on commercial scale over a 32 PLUS year tenure till date Feb 2023, Around 35 plus products in his career. He has good knowledge of IPM, GMP, Regulatory aspects, he has several International patents published worldwide . He has good proficiency in Technology transfer, Spectroscopy, Stereochemistry, Synthesis, Polymorphism etc., He suffered a paralytic stroke/ Acute Transverse mylitis in Dec 2007 and is 90 %Paralysed, He is bound to a wheelchair, this seems to have injected feul in him to help chemists all around the world, he is more active than before and is pushing boundaries, He has 100 million plus hits on Google, 2.5 lakh plus connections on all networking sites, 100 Lakh plus views on dozen plus blogs, 227 countries, 7 continents, He makes himself available to all, contact him on +91 9323115463, email amcrasto@gmail.com, Twitter, @amcrasto , He lives and will die for his family, 90% paralysis cannot kill his soul., Notably he has 38 lakh plus views on New Drug Approvals Blog in 227 countries......https://newdrugapprovals.wordpress.com/ , He appreciates the help he gets from one and all, Friends, Family, Glenmark, Readers, Wellwishers, Doctors, Drug authorities, His Contacts, Physiotherapist, etc He has total of 32 International and Indian awards

Verified Services

View Full Profile →

Recent Posts

Pfizer second quarter earnings beat estimates


marciocbarra's avatar

July 30 2013 | By Márcio Barra

Pfizer reported today their second-quarter profits, beating analysts’ estimates as it prepares to rearrange its business operations. Earnings excluding one-time items were 56 cents a share, compared with the 55 cents average estimated by Bloomberg and Thomson Reuters I/B/E/S. Net income rose more than fourfold to $14.1 billion, or $1.98 a share, from $3.25 billion, or 43 cents last year. Revenue however, fell 7% to $12.97 billion, compared with the $13.03 billion analysts estimated.

View original post 628 more words

Kiran Mazumdar-Shaw, chairman and managing director of Indian biopharma giant Biocon propels company to clock revenue worth $121 mn


Kiran Mazumdar-Shaw, chairman and managing director, Biocon.

Kiran Mazumdar Shaw: She has the odd passion—artwork, horses—but it’s Biocon that really gives her joy

What do our other billionairesses like to splurge on? Kiran’s abiding passion, apart from her work, are horses and paintings—she particularly enjoys collecting the works of Yusuf Arakkal and S.G. Vasudev. Sailoja confesses she loves Louis Vuitton purses and diamond and gold jewellery. “But I haven’t bought any great jewellery for two years now,” she says. Shobhana admits to a weakness for designer watches and bags, as well as light, trendy and stylish fashion jewellery which is not necessarily very expensive. Ekta loves dressing up—but of course her biggest pleasure comes from watching her audience ratings soar.

For most, making billions is not what drives them. Sulajja, who recently sold a 15 per cent stake in her company to Anil Ambani’s Reliance Capital, could be speaking for all of them when she sums up: “Neither me nor my family has been about money. That’s not how we relate to people either. I appreciate that I have certain comforts and don’t have to struggle as much as some for basics, but beyond that we’re just simple hard-working people.”


By Paromita Shastri with Charubala Annuncio, Archana Rai and Madhavi Tata

FROM

Kiran Mazumdar-Shaw thinks her training in brewing helped her found biotech company Biocon.

Kiran Mazumdar-Shaw is one of the richest women in India. She is the founder of Biocon, a biotech company and Asia’s largest insulin maker.

But the chairman and managing director attributes her success to her go-getting nature rather than entrepreneurial spirit.

Ms Mazumdar-Shaw originally trained to become a brewer in Australia, before returning to India to follow in her father’s footsteps as a brew-master.

But she struggled to find a job on her return and recalls the industry wasn’t ready for a strong female presence. “The brewing industry is a very, very male dominated industry” she says. “It’s a male bastion.”

Opportunity

She refused to be thwarted. “I really wanted to do something with my life,” she remembers. It was this rebellious streak that inspired her to start her own company, although she admits the opportunity was more by chance.

“This is why I call myself an accidental entrepreneur – because it was an accidental encounter with another entrepreneur… who wanted to set up shop in India and… asked me whether I would be able to partner this venture,” she says.

The chance meeting persuaded Ms Mazumdar-Shaw to launch into the business of developing and making enzymes.

She says she wasn’t daunted by the transition from brewery to biotech. “If you think about brewing, it is biotechnology. And I would say that I was a technologist at heart. So whether I… fermented beer or whether I fermented enzymes, the base technology was the same.”

Female entrepreneurs

Gradually she moved the business into manufacturing medicines. The original development and sale of enzymes gave her the cash flow to fund the research and production of pharmaceutical drugs.

She feels this was a canny business move.

“There was no venture funding in India, so it forced me to create a business model that was based on revenues and profits.”

She adds: “That got us into a very different kind of format… to the typical biotech format, which depends largely on VC [venture capitalist] funding.”

But she admits that even as a female entrepreneur she still had to contend with the old issue of gender prejudice.

“Banks were very fearful of lending to a woman because I was considered high risk.”

Her age and the relatively new area of biotechnology didn’t help matters: “I was young, I was twenty-five years old… banks were very nervous about lending to young entrepreneurs because they felt we didn’t have the business experience… and then I had… this strange business called biotechnology which no one understood.”

Kiran Mazumdar-Shaw says her previous experience of failure gave her the resilience to persevere.

Biocon, BangaloreBangalore has developed from a quiet city into South India’s technology hub

“I was determined to make a success of this business because I had failed to be a brew master,” she admits.

“I just kept knocking at people’s doors and I said ‘look you’ve got to… help me’. I did manage to persuade a few people to stand by me and fund me and that’s how I got the business started.”

Bangalore

Ms Mazumdar-Shaw started Biocon in 1978 when Bangalore had yet to become the hub of technology of South India.

She remembers it as a “sleepy old retired city” but says it was an exciting place to start experimenting.

“We were first generation entrepreneurs trying to start high technology businesses… whether it was IT and services, or whether it was my biotech business… that was a time where there was tremendous energy, you know, being unleashed.”

Now she says the transformation of Bangalore into a “vibrant high growth centre” reflects the paradox of India. She believes the contrast between high wealth and extreme poverty – often within a few kilometres of each other – is the result of a failure to follow an inclusive economic agenda.

Social Entrepreneurship

Aside from running Biocon, Kiran Mazumdar-Shaw has also undertaken some social entrepreneurship projects.

One area she’s become involved with is public health. “I am very concerned about the fact that India as a country does not have a national health system, and I am determined to try and influence the government to really build a national health system for the country,” she says.

In the meantime, she has created a network of small clinics to provide some basic health care in rural areas.

BIOCON

  • Turnover (2010): Rs 2400 Cr, approx 535 million US dollars
  • Number of employees: 5000
  • HQ Location: Bangalore
  • Year founded: 1978
  • Ownership: Listed on BSE & NSE (India)

It’s a part of a “micro health insurance programme” funded largely by her, with small donations from those using it.

Pick yourself up

Kiran Mazumdar-Shaw says self-confidence is an important factor in entrepreneurship.

“A can-do attitude” is essential because obstacles and difficulties are inevitable. “I’ve had many failures in terms of technological… business… and even research failures,” she explains.

“I really believe that entrepreneurship is about being able to face failure, manage failure and succeed after failing.”

The key is to be able to tell the difference between total failure and setbacks which can be overcome.

“I think in my particular case, I’ve seen that failures are not absolute. That you can build and modify those failures to succeed.”

 

Kiran Mazumdar-Shaw, chairman and managing director, Biocon.
Indian biopharma giant Biocon reported healthy growth of 22 percent for Q1 FY14 riding on the back of an increased geographical footprint in the emerging markets

Bangalore: Indian biopharma giant Biocon reported healthy growth of 22 percent for Q1 FY14. The firm clocked revenues worth $121 million (Rs723 crore), EBITDA of $29.50 million (Rs175 crore); and profit after tax (PAT) of $15.80 million (Rs94 crore).

Read more at: http://www.biospectrumasia.com/biospectrum/news/192549/how-biocon-clock-revenue-worth-usd121-mn#.UfdqX6I3CSo

Biocon’s India-focused branded formulations vertical as well as research services continue to grow at a steady pace

………
check this video

…..

Indian Pharma Market Needs Strong Regulatory Set-up: Kiran Mazumdar-Shaw


Kiran Mazumdar Shaw

Kiran Mazumdar-Shaw, MD, BIOCON

Indian Pharma Market Needs Strong Regulatory Set-up:   Kiran Mazumdar-Shaw, MD, BIOCON

Biocon is looking at gaining market share and improving its margins with a greater focus on its product mixes and organizational efficiencies. Biocon Chairman and Managing Director Kiran Mazumdar-Shaw tells Financial Express that the company has outpaced the market, despite various challenges and that the pharmaceutical market needs to have a more robust regulatory set-up. Edited excerpts:

READ ALL AT

http://kiranmazumdarshaw.blogspot.in/2013/07/indian-pharma-market-needs-strong.html

………………

Serum Institute of India acquires rights to TB vaccine


Serum Institute of India acquires rights to TB vaccine

Serum Institute of India, a Pune-based manufacturer of vaccines, is planning on taking a promising vaccine – originally developed in Germany – and introducing it into the clinic. Studies have shown that the new vaccine is more effective and better tolerated than currently available options.

By signing a contract with Hannover-based Vakzine Projekt Management (VPM), Serum has secured the licence to the various patents and technologies related to the…

Click here to read more

…..

Natural Remedies for Erectile Dysfunction (ED) & Impotence


WAIT FOR VIDEO TO LOAD

……………………………………

Indian Pharma Market Needs Strong Regulatory Set-up: Kiran Mazumdar-Shaw


DR ANTHONY MELVIN CRASTO Ph.D's avatarDRUG REGULATORY AFFAIRS INTERNATIONAL

Kiran Mazumdar Shaw

Kiran Mazumdar-Shaw, MD, BIOCON

 

Indian Pharma Market Needs Strong Regulatory Set-up:   Kiran Mazumdar-Shaw, MD, BIOCON

 

Biocon is looking at gaining market share and improving its margins with a greater focus on its product mixes and organizational efficiencies. Biocon Chairman and Managing Director Kiran Mazumdar-Shaw tells Financial Express that the company has outpaced the market, despite various challenges and that the pharmaceutical market needs to have a more robust regulatory set-up. Edited excerpts:

READ ALL AT

http://kiranmazumdarshaw.blogspot.in/2013/07/indian-pharma-market-needs-strong.html

View original post

Watermelon Juice Prevents Aching Muscles Food Chemistry: The amino acid L-citrulline found in the fruit could help athletes avoid muscle soreness after a hard workout


DR ANTHONY MELVIN CRASTO Ph.D's avatarGreen Chemistry International

Photo of watermelon juice smoothie in tall glass
The Next Sports Drink?
Watermelon drinks, like this smoothie, could help cut down on muscle soreness after intense exercise.
Credit: Shutterstock
Before taking a long bike ride on a hot summer day, have some watermelon: The juicy fruit may ward off muscle pains. Researchers report that people who drank watermelon juice before exercising felt less sore the next day than those who drank a pink placebo beverage (J. Agric. Food Chem. 2013, DOI: 10.1021/jf400964r). They also found that cells absorb the presumed active ingredient, L-citrulline, more readily from unpasteurized watermelon juice than from plain water spiked with the compound, suggesting the natural source is the optimal delivery
medium.

View original post

India seeks to cancel Roche cancer patent


india-may-revoke-roche-s-breast-cancer-drug-s-patent-using-section-66-of-the-indian-patents-act

India may revoke Roche’s breast cancer drug’s patent using section 66 of the Indian Patents Act

http://www.biospectrumasia.com/biospectrum/news/192436/india-seeks-cancel-roche-cancer-patent#.UfXtuaI3CSo

India’s health ministry is looking to revoke Roche’s breast cancer drug’s patent in public interest using powers under section 66 of the Indian Patents Act India may revoke Roche’s breast cancer drug’s patent using section 66 of the Indian Patents Act Related Articles Oramed gets Japanese patent for protein delivery Cipla wins patent case against Roche Alchemia cancer drug gets US patent protection Alchemia gets US patent for oncology platform technology New Delhi: India’s health ministry has asked for a cancellation of patent to Roche’s breast cancer medicine Trastuzumab, using a rarest-of-the-rare provision in the Indian Patents Act.
Read more at: http://www.biospectrumasia.com/biospectrum/news/192436/india-seeks-cancel-roche-cancer-patent#.UfXtuaI3CSo

Kyowa Hakko Kirin Korea begins patient recruitment in phase I/II study of BIW-8962 in lung cancer


Kyowa Hakko Kirin Korea begins patient recruitment in phase I/II study of BIW-8962 in lung cancer

http://www.kyowa-kirin.com/news_releases/2011/pdf/e20110802_04.pdf

http://clinicaltrials.gov/ct2/show/NCT01898156

Kyowa Hakko Kirin Korea Co., Ltd

This Phase 1/2 study is designed to assess the following: safety and tolerability of BIW-8962, Dose Limiting Toxicities (DLTs), Maximum Tolerated Dose (MTD), Recommended Phase 2 Dose (RP2D) in Phase 1 and preliminary efficacy in Phase 2 in subjects with advanced/recurrent lung cancer or mesothelioma.

http://www.myeloma.org.uk/patient-information/drug-development/hcp-drug-scanner/biw-8962/

UK regulator approves access to Revolade drug after three-year process


25 July 2013

The National Institute for Health and Care Excellence (NICE) in the UK has recommended immune disorder drug Revolade for use on the NHS after a process of three and a half years.

The GSK once-daily oral treatment is now available to adult patients in England and Wales living with chronic immune (idiopathic) thrombocytopenic purpura (cITP), an immune disorder associated with low-blood platelet counts.

In patients with cITP, the immune system prematurely destroys platelets or impairs their production so that platelets are lost from the circulation faster than they can be replaced from the bone marrow, where they are made.

This results in patients developing mild bruising or serious bleeding, which affects their quality of life and, in some instances, may be fatal.

It is estimated that cITP currently affects 50 in 100,000 people in the UK.

The only other licensed TPO-RA recommended by NICE is romiplostim, which is given in the form of a weekly injection.

The Royal London Hospital’s clinical director for pathology Prof Adrian Newland said: “I was very pleased to see that NICE has recognised the clinical value and cost-effectiveness of eltrombopag in their guidance.

“We now have an important addition to the treatment options for patients with severe or refractory disease.”

“With eltrombopag, we hope to ultimately make a meaningful difference in the quality of life of cITP patients and contribute to potential savings for the NHS.”

Revolade is an oral thrombopoietin receptor agonist (TPO-RA) that stimulates the growth and maturation of cells in the bone marrow (megakaryocytes) that produce platelets, increasing platelet production.

When added to conventional immunosuppressive therapy, Revolade, also known as eltrombopag, increases response rates compared with placebo and in some patients.

GlaxoSmithKline UK general manager Erik Van Snippenberg said: “This has been a lengthy three and a half year long appraisal process. We are pleased that NICE has recommended eltrombopag and that the small number of cITP patients in England and Wales are granted access to an alternative treatment option offering the benefit of oral convenience.

“With eltrombopag, we hope to ultimately make a meaningful difference in the quality of life of cITP patients and contribute to potential savings for the NHS.”

 

Follow New Drug Approvals on WordPress.com

Enter your email address to follow this blog and receive notifications of new posts by email.

Join 37.8K other subscribers

ORGANIC SPECTROSCOPY

Read all about Organic Spectroscopy on ORGANIC SPECTROSCOPY INTERNATIONAL 

DISCLAIMER

I , Dr A.M.Crasto is writing this blog to share the knowledge/views, after reading Scientific Journals/Articles/News Articles/Wikipedia. My views/comments are based on the results /conclusions by the authors(researchers). I do mention either the link or reference of the article(s) in my blog and hope those interested can read for details. I am briefly summarising the remarks or conclusions of the authors (researchers). If one believe that their intellectual property right /copyright is infringed by any content on this blog, please contact or leave message at below email address amcrasto@gmail.com. It will be removed ASAP