New Drug Approvals

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DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 36Yrs Exp. in the feld of Organic Chemistry,Working for AFRICURE PHARMA as ADVISOR earlier with GLENMARK PHARMA at Navi Mumbai, INDIA. Serving chemists around the world. Helping them with websites on Chemistry.Million hits on google, NO ADVERTISEMENTS , ACADEMIC , NON COMMERCIAL SITE, world acclamation from industry, academia, drug authorities for websites, blogs and educational contribution, ........amcrasto@gmail.com..........+91 9323115463, Skype amcrasto64

DR ANTHONY MELVIN CRASTO Ph.D

DR ANTHONY MELVIN CRASTO, Born in Mumbai in 1964 and graduated from Mumbai University, Completed his Ph.D from ICT, 1991,Matunga, Mumbai, India, in Organic Chemistry, The thesis topic was Synthesis of Novel Pyrethroid Analogues, Currently he is working with AFRICURE PHARMA, ROW2TECH, NIPER-G, Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Govt. of India as ADVISOR, earlier assignment was with GLENMARK LIFE SCIENCES LTD, as CONSUlTANT, Retired from GLENMARK in Jan2022 Research Centre as Principal Scientist, Process Research (bulk actives) at Mahape, Navi Mumbai, India. Total Industry exp 32 plus yrs, Prior to joining Glenmark, he has worked with major multinationals like Hoechst Marion Roussel, now Sanofi, Searle India Ltd, now RPG lifesciences, etc. He has worked with notable scientists like Dr K Nagarajan, Dr Ralph Stapel, Prof S Seshadri, etc, He did custom synthesis for major multinationals in his career like BASF, Novartis, Sanofi, etc., He has worked in Discovery, Natural products, Bulk drugs, Generics, Intermediates, Fine chemicals, Neutraceuticals, GMP, Scaleups, etc, he is now helping millions, has 9 million plus hits on Google on all Organic chemistry websites. His friends call him Open superstar worlddrugtracker. His New Drug Approvals, Green Chemistry International, All about drugs, Eurekamoments, Organic spectroscopy international, etc in organic chemistry are some most read blogs He has hands on experience in initiation and developing novel routes for drug molecules and implementation them on commercial scale over a 32 PLUS year tenure till date Feb 2023, Around 35 plus products in his career. He has good knowledge of IPM, GMP, Regulatory aspects, he has several International patents published worldwide . He has good proficiency in Technology transfer, Spectroscopy, Stereochemistry, Synthesis, Polymorphism etc., He suffered a paralytic stroke/ Acute Transverse mylitis in Dec 2007 and is 90 %Paralysed, He is bound to a wheelchair, this seems to have injected feul in him to help chemists all around the world, he is more active than before and is pushing boundaries, He has 100 million plus hits on Google, 2.5 lakh plus connections on all networking sites, 100 Lakh plus views on dozen plus blogs, 227 countries, 7 continents, He makes himself available to all, contact him on +91 9323115463, email amcrasto@gmail.com, Twitter, @amcrasto , He lives and will die for his family, 90% paralysis cannot kill his soul., Notably he has 38 lakh plus views on New Drug Approvals Blog in 227 countries......https://newdrugapprovals.wordpress.com/ , He appreciates the help he gets from one and all, Friends, Family, Glenmark, Readers, Wellwishers, Doctors, Drug authorities, His Contacts, Physiotherapist, etc He has total of 32 International and Indian awards

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Unleashing the watchdog protein: Research opens door to new drug therapies for Parkinson’s disease

May 17, 2013 11:59 am / Leave a comment

Syn-Org-Chemist

Unleashing the watchdog protein: Research opens door to new drug therapies for Parkinson’s disease.

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Gene offers clues to new treatments for a harmful blood clotting disorder

May 17, 2013 11:47 am / Leave a comment

Syn-Org-Chemist

Gene offers clues to new treatments for a harmful blood clotting disorder.

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Whole walnuts and their extracted oil improve cardiovascular disease risk

May 17, 2013 11:45 am / Leave a comment

Syn-Org-Chemist

Whole walnuts and their extracted oil improve cardiovascular disease risk.

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Novel isocitrate dehydrogenases 1 and 2 inhibitors prevent the growth of brain and blood tumors

May 17, 2013 4:09 am / 1 Comment on Novel isocitrate dehydrogenases 1 and 2 inhibitors prevent the growth of brain and blood tumors

Silencing a Tumorigenic Catalyst

Novel isocitrate dehydrogenases 1 and 2 inhibitors prevent the growth of brain and blood tumors

Catenane synthesis is studied with the aim of producing molecular switches for use in molecular memory devices

May 17, 2013 4:07 am / 1 Comment on Catenane synthesis is studied with the aim of producing molecular switches for use in molecular memory devices

Making Molecular Switches

Catenane synthesis is studied with the aim of producing molecular switches for use in molecular memory devices

Magnetic Nanoparticles Detect Pathogens

May 17, 2013 4:06 am / Leave a comment

Magnetic Nanoparticles Detect Pathogens

A novel iron oxide nanoparticle-based system detects pathogens with high sensitivity, specificity, and rapidity

Nanomachine Drug Delivery

May 17, 2013 4:02 am / 1 Comment on Nanomachine Drug Delivery

Nanomachine Drug Delivery

A sensing–actuating nanomachine based on Janus Au–mesoporous silica nanoparticles for enzyme-controlled cargo release

Congress, FDA Should Look to Existing Technology to Make Pharmacy Compounding Safer

May 17, 2013 3:48 am / Leave a comment

Last fall’s deadly meningitis outbreak linked to contaminated steroid injections is a tragic reminder of the risk of errors inherent in manual pharmacy medication compounding. Unsanitary conditions at the Massachusetts compounding pharmacy that made the injections resulted in fungal contamination of the drugs. The resulting outbreak sickened nearly 700 people in 19 states, and killed more than 40.

read all at

http://www.pharmpro.com/blogs/2013/03/congress-fda-should-look-existing-technology-make-pharmacy-compounding-safer

New Drug May Help Immune System Fight Cancer

May 17, 2013 3:37 am / 1 Comment on New Drug May Help Immune System Fight Cancer

May 16, 2013 — An experimental drug that taps the power of the body’s immune system to fight cancer is shrinking tumors in patients for whom other treatments have failed, an early study shows.

read all at

http://www.drugs.com/news/new-may-help-immune-fight-cancer-44582.html

Roche files next-generation Rituxan in USA, EU

May 17, 2013 12:56 am / 1 Comment on Roche files next-generation Rituxan in USA, EU

Roche files next-generation Rituxan in USA, EU

Roche has filed obinutuzumab on both sides of the Atlantic to treat chronic lymphocytic leukaemia.May 16, 2013

read all at

http://www.pharmatimes.com/Article/13-05-16/Roche_files_next-generation_Rituxan_in_USA_EU.aspx

CHEMICAL NAMES

1. Immunoglobulin G1, anti-(human CD20 (

antigen)) (human-mouse monoclonal GA101

heavy chain), disulfide with human-mouse monoclonal GA101k chain, dimer

http://www.ama-assn.org/resources/doc/usan/obinutuzumab.pdf

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Mevrometostat
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Maritupirdine CAS 1025725-91-0 MF C21H24N2 MW304.4 g/mol 2,3,4,5-TETRAHYDRO-2,8-DIMETHYL-5-PHENETHYL-1H-PYRIDO(4,3-B)INDOLE 2,8-dimethyl-5-(2-phenylethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoleserotonin receptor antagonist, antidepressant, AVN-101, AVN 101, CD 008 0045, 6MHR5IV28S MARITUPIRDINE is a small molecule drug with…
Luvometinib
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Laselipag
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