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ORGANIC SPECTROSCOPY

Read all about Organic Spectroscopy on ORGANIC SPECTROSCOPY INTERNATIONAL 

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DR ANTHONY MELVIN CRASTO Ph.D

DR ANTHONY MELVIN CRASTO Ph.D

DR ANTHONY MELVIN CRASTO, Born in Mumbai in 1964 and graduated from Mumbai University, Completed his Ph.D from ICT, 1991,Matunga, Mumbai, India, in Organic Chemistry, The thesis topic was Synthesis of Novel Pyrethroid Analogues, Currently he is working with AFRICURE PHARMA, ROW2TECH, NIPER-G, Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Govt. of India as ADVISOR, earlier assignment was with GLENMARK LIFE SCIENCES LTD, as CONSUlTANT, Retired from GLENMARK in Jan2022 Research Centre as Principal Scientist, Process Research (bulk actives) at Mahape, Navi Mumbai, India. Total Industry exp 32 plus yrs, Prior to joining Glenmark, he has worked with major multinationals like Hoechst Marion Roussel, now Sanofi, Searle India Ltd, now RPG lifesciences, etc. He has worked with notable scientists like Dr K Nagarajan, Dr Ralph Stapel, Prof S Seshadri, etc, He did custom synthesis for major multinationals in his career like BASF, Novartis, Sanofi, etc., He has worked in Discovery, Natural products, Bulk drugs, Generics, Intermediates, Fine chemicals, Neutraceuticals, GMP, Scaleups, etc, he is now helping millions, has 9 million plus hits on Google on all Organic chemistry websites. His friends call him Open superstar worlddrugtracker. His New Drug Approvals, Green Chemistry International, All about drugs, Eurekamoments, Organic spectroscopy international, etc in organic chemistry are some most read blogs He has hands on experience in initiation and developing novel routes for drug molecules and implementation them on commercial scale over a 32 PLUS year tenure till date Feb 2023, Around 35 plus products in his career. He has good knowledge of IPM, GMP, Regulatory aspects, he has several International patents published worldwide . He has good proficiency in Technology transfer, Spectroscopy, Stereochemistry, Synthesis, Polymorphism etc., He suffered a paralytic stroke/ Acute Transverse mylitis in Dec 2007 and is 90 %Paralysed, He is bound to a wheelchair, this seems to have injected feul in him to help chemists all around the world, he is more active than before and is pushing boundaries, He has 100 million plus hits on Google, 2.5 lakh plus connections on all networking sites, 100 Lakh plus views on dozen plus blogs, 227 countries, 7 continents, He makes himself available to all, contact him on +91 9323115463, email amcrasto@gmail.com, Twitter, @amcrasto , He lives and will die for his family, 90% paralysis cannot kill his soul., Notably he has 38 lakh plus views on New Drug Approvals Blog in 227 countries......https://newdrugapprovals.wordpress.com/ , He appreciates the help he gets from one and all, Friends, Family, Glenmark, Readers, Wellwishers, Doctors, Drug authorities, His Contacts, Physiotherapist, etc He has total of 32 International and Indian awards

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About Hepatitis

mynaturalcures's avatarMy Natural Cures

Here are the most important information about hepatitis.

Five different hepatitis viruses have been identified: type A; type B; type C; type D, or delta virus; and type E. Type A is probably the most prevalent type of viral hepatitis worldwide, followed by types B, E, C, and D.

Hepatitis A and E are transmitted through fecally contaminated food or water. Other modes of transmission include needle sharing among intravenous drug abusers; sexual contact; maternal transmission; and transmission by blood transfusion.

A simple blood test is used to determine that a person has one or more of the different types of hepatitis.

Acute hepatitis is typically characterized by flu-like symptoms (including fever, headaches, fatigue, nausea and vomiting) and jaundice. Chronic hepatitis is often asymptomatic.

Vaccines are available to protect against hepatitis A and B. Additionally, immune globulin for hepatitis A or hepatitis B is recommended when someone has been exposed…

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होम्योपैथिक दवा ; मूलेन आयल ; कान के सभी रोगों की अचूक और सटीक दवा ; MULLEIN OIL ; THE HOMOEOPATHIC REMEDIY FOR ALL “EAR” DISORDERS ; THE MOST SAFEST NATURAL REMEDY

Dr.D.B.Bajpai's avatar**आधुनिक युग आयुर्वेद ** ई०टी०जी० आयुर्वेदास्कैन ** DIGITAL AYURVEDA TRIDOSHO SCANNER**AYURVED H. T. L. WHOLE-BODY SCANNER**आयुषव्यूज रक्त केमिकल केमेस्ट्री परीक्षण अनालाइजर ** डिजिटल हैनीमेनियन होम्योपैथी स्कैनर **

होम्योपैथिक चिकित्सा विग्यान मे ऐसी बहुत सी दवाओ की भरमार और बहुतायत है जो कठिन से कठिन और लाइलाज बीमारी के इलाज के लिये परम उपयोगी है /

लेकिन समस्या यह है कि इतनी प्रभाव्कारी चिकित्सा विग्यान के होते हुये भी लोग और देश के जन मानस को जानकारी के अभाव मे पता ही नही है कि जिन बीमारियो को जिसे वे समझते है कि कोई इलाज नही है, ऐसी इन सभी बीमारियों का इलाज मौजूद है और सटीक और अचूक इलाज है /

होम्योपैथी की MULLEIN OIL एक ऐसी दवा है जिसे “कान” या “INTERNAL EAR ” से सम्बन्धित बीमारियो मे उपयोग कर्ते है /

मूलेन आयल MULLEIN OIL द्वा का नाम है और इसी नाम से बज़ार मे होम्योपैथिक स्टोरर्स मे मिलती है /

यह होम्योपैथिक दवा VERBASCUM नाम के यूरोप महाद्वीप मे पैदा होने वाले एक पेड़ से पैदा होने वाले फूलों से बनाते है / Verbascum…

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Molecular biology mystery unravelled

Lyranara.me's avatarLyra Nara Blog

Molecular biology mystery unravelled

The nature of the machinery responsible for the entry of proteins into cell membranes has been unravelled by scientists, who hope the breakthrough could ultimately be exploited for the design of new anti-bacterial drugs. Groups of researchers from the University of Bristol and the European Molecular Biology Laboratory (EMBL) used new genetic engineering technologies to reconstruct and isolate the cell’s protein trafficking machinery.

Its analysis has shed new light on a process which had previously been a mystery for molecular biologists.

The findings, published today in the Proceedings of the National Academy of Sciences(PNAS), could also have applications for synthetic biology – an emerging field of science and technology, for the development of novel membrane proteins with useful activities.

Proteins are the building blocks of all life and are essential for the growth of cells and tissue repair. The proteins in the membrane typically help the cell…

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An off-switch for drugs’ toxic side effects

Lyranara.me's avatarLyra Nara Blog

When medications linger in the human body, they sometimes produce toxic side effects.  Professor Alexandros Makriyannis, the George D. Behrakis Trustee Chair in Pharmaceutical Biotechnology and Director of the Center for Drug Discovery at Northeastern, explained that many things can happen to a drug inside our bodies once it is ingested. For instance, the drug can be modified into other byproducts with their own undesirable and unpredictable effects. Or it can remain embedded in the body’s fatty tissues and then be slowly released into the circulatory system.

“If you had a way of controlling how long this drug sits in the body,” Makriyannis said, “that would be a beneficial effect. It would be a safer drug.”

In research recently published in the Journal of Medicinal Chemistry and Medicinal Chemistry Letters, Makriyannis and his team present not just one such drug but a whole series of them. “We call…

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Quantum biology: Algae evolved to switch quantum coherence on and off

Lyranara.me's avatarLyra Nara Blog

Quantum biology: Algae evolved to switch quantum coherence on and off

A scanning electron microscope image of cryptophytes. A UNSW Australia-led team has discovered how cryptophytes that survive in very low levels of light are able to switch on and off a weird quantum phenomenon that occurs during photosynthesis. Credit: CSIRO

A UNSW Australia-led team of researchers has discovered how algae that survive in very low levels of light are able to switch on and off a weird quantum phenomenon that occurs during photosynthesis.

The function in the algae of this quantum effect, known as coherence, remains a mystery, but it is thought it could help them harvest energy from the sun much more efficiently. Working out its role in a living organism could lead to technological advances, such as better organic solar cells and quantum-based electronic devices.

The research is published in the journal Proceedings of the National Academy of Sciences.

It is part of an emerging field called…

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Ebola outbreak in West Africa ‘out of control’

atasteofcreole's avatarAtasteofcreole's Blog

http://www.foxnews.com/health/2014/06/20/ebola-outbreak-in-west-africa-out-control/?intcmp=latestnews

A senior official for Doctors Without Borders says the Ebola outbreak ravaging West Africa is “totally out of control” and that the medical group is stretched to the limit in its capacity to respond.

Bart Janssens, the director of operations for the group in Brussels, said Friday that international organizations and the governments involved need to send in more health experts and increase public education messages about how to stop the spread of the disease.

Janssens said the outbreak is far from over and will probably end up as the most deadly on record.

According to the latest figures from the World Health Organization, Ebola has already been linked to more than 330 deaths in Guinea, Sierra Leone and Liberia.

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Is the Warburg Effect the Cause or the Effect of Cancer: A 21st Century View?

larryhbern's avatarLeaders in Pharmaceutical Business Intelligence Group, LLC, Doing Business As LPBI Group, Newton, MA

Is the Warburg Effect the Cause or the Effect of Cancer: A 21st Century View?

Author: Larry H. Bernstein, MD, FCAP  

A Critical Review

What is the Warburg effect?

“Warburg Effect” describes the preference of glycolysis and lactate fermentation rather than oxidative phosphorylation for energy production in cancer cells. Mitochondrial metabolism is an important and necessary component in the functioning and maintenance of the organelle, and accumulating evidence suggests that dysfunction of mitochondrial metabolism plays a role in cancer. Progress has demonstrated the mechanisms of the mitochondrial metabolism-to-glycolysis switch in cancer development and how to target this metabolic switch.
In vertebrates, food is digested and supplied to cells mainly in the form of glucose. Glucose is broken down further to make Adenosine Triphosphate (ATP) by two pathways. One is via anaerobic metabolism occurring in the cytoplasm, also known as glycolysis. The major physiological significance of glycolysis lies in making ATP…

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A better imager for identifying tumors

Lyranara.me's avatarLyra Nara Blog

A better imager for identifying tumors

This is (a) Optical and mechanical structure of the customized lens with aperture filter and (b) the photograph of the assembled lens, with a quarter for comparison. Credit: Optics Letters

Before they excise a tumor, surgeons need to determine exactly where the cancerous cells lie. Now, research published today in The Optical Society’s (OSA) journal Optics Letters details a new technique that could give surgeons cheaper and more lightweight tools, such as goggles or hand-held devices, to identify tumors in real time in the operating room.

The new technology, developed by a team at the University of Arizona and Washington University in St. Louis, is a dual-mode imager that combines two systems—near-infrared fluorescent imaging to detect marked cancer cells and visible light reflectance imaging to see the contours of the tissue itself—into one small, lightweight package approximately the size of a quarter in diameter, just 25 millimeters across.

“Dual modality is…

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Developing an improved liposuction technique that melts fat

Lyranara.me's avatarLyra Nara Blog

Although liposuction is one of the most common and well-established cosmetic surgery procedures in the U.S., it still has its drawbacks. But a new biomedical start-up says it may have found a novel way to improve the procedure using gold nanoparticles to literally melt fat, reports Chemical & Engineering News (C&EN), the weekly news magazine of the American Chemical Society.

Lauren K. Wolf, an associate editor at C&EN, explains that during the most common type of liposuction procedure, a surgeon inserts a sharp-edged needle through an incision, moves it back and forth to break up fat cells and then vacuums them out. The problem is the procedure isn’t selective, and sometimes connective tissue and nerves get removed along with the fat cells. Liposuction patients often suffer from bruising, long recovery times and lumpiness that has to be corrected with a second procedure. To address the surgery’s problems, a…

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Do salamanders hold the key to limb regeneration?

Lyranara.me's avatarLyra Nara Blog

Limb regeneration: Do salamanders hold the key?

This is an image of a salamander (the newt Notophthalmus viridescens). Credit: University College London

The secret of how salamanders successfully regrow body parts is being unravelled by University College London researchers in a bid to apply it to humans.

For the first time, researchers have found that the ‘ERK pathway’ must be constantly active for salamander cells to be reprogrammed, and hence able to contribute to the regeneration of different body parts.

The team identified a key difference between the activity of this pathway in salamanders and mammals, which helps us to understand why humans can’t regrow limbs and sheds light on how regeneration of human cells can be improved.

The study published in Stem Cell Reports today, demonstrates that the ERK pathway is not fully active in mammalian cells, but when forced to be constantly active, gives the cells more potential for reprogramming and regeneration. This could…

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