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DR ANTHONY MELVIN CRASTO, Born in Mumbai in 1964 and graduated from Mumbai University, Completed his Ph.D from ICT, 1991,Matunga, Mumbai, India, in Organic Chemistry, The thesis topic was Synthesis of Novel Pyrethroid Analogues, Currently he is working with AFRICURE PHARMA, ROW2TECH, NIPER-G, Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Govt. of India as ADVISOR, earlier assignment was with GLENMARK LIFE SCIENCES LTD, as CONSUlTANT, Retired from GLENMARK in Jan2022 Research Centre as Principal Scientist, Process Research (bulk actives) at Mahape, Navi Mumbai, India. Total Industry exp 32 plus yrs, Prior to joining Glenmark, he has worked with major multinationals like Hoechst Marion Roussel, now Sanofi, Searle India Ltd, now RPG lifesciences, etc. He has worked with notable scientists like Dr K Nagarajan, Dr Ralph Stapel, Prof S Seshadri, etc, He did custom synthesis for major multinationals in his career like BASF, Novartis, Sanofi, etc., He has worked in Discovery, Natural products, Bulk drugs, Generics, Intermediates, Fine chemicals, Neutraceuticals, GMP, Scaleups, etc, he is now helping millions, has 9 million plus hits on Google on all Organic chemistry websites. His friends call him Open superstar worlddrugtracker. His New Drug Approvals, Green Chemistry International, All about drugs, Eurekamoments, Organic spectroscopy international, etc in organic chemistry are some most read blogs He has hands on experience in initiation and developing novel routes for drug molecules and implementation them on commercial scale over a 32 PLUS year tenure till date Feb 2023, Around 35 plus products in his career. He has good knowledge of IPM, GMP, Regulatory aspects, he has several International patents published worldwide . He has good proficiency in Technology transfer, Spectroscopy, Stereochemistry, Synthesis, Polymorphism etc., He suffered a paralytic stroke/ Acute Transverse mylitis in Dec 2007 and is 90 %Paralysed, He is bound to a wheelchair, this seems to have injected feul in him to help chemists all around the world, he is more active than before and is pushing boundaries, He has 100 million plus hits on Google, 2.5 lakh plus connections on all networking sites, 100 Lakh plus views on dozen plus blogs, 227 countries, 7 continents, He makes himself available to all, contact him on +91 9323115463, email, Twitter, @amcrasto , He lives and will die for his family, 90% paralysis cannot kill his soul., Notably he has 38 lakh plus views on New Drug Approvals Blog in 227 countries...... , He appreciates the help he gets from one and all, Friends, Family, Glenmark, Readers, Wellwishers, Doctors, Drug authorities, His Contacts, Physiotherapist, etc He has total of 32 International and Indian awards

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Triphala : A Digestive Miracle

Emblica officinalis

Terminalia bellirica


Terminalia chebula

Triphala (/trˈfɑːlə/ or /trˈfælə/Hindi/Sanskrit: त्रिफला, triphalā [trɪˈpʰɐlaː], “three fruits”)[1] is an Ayurvedic[2] herbal rasayana formula consisting of equal parts of three myrobalans, taken without seed: Amalaki (Emblica officinalis), Bibhitaki (Terminalia bellirica), and Haritaki (Terminalia chebula).[1]

Medicinal use

In traditional Ayurvedic medicine, Triphala is used for:

  • immune system stimulation[3]
  • improvement of digestion[4][1]
  • relief of constipation[4][1]
  • gastrointestinal tract cleansing[4]
  • relief of gas[1]
  • treatment of diabetes[1]
  • treatment of eye disease[1]

These health claims have not been yet tested in clinical trials. Even within the practice of Ayurvedic medicine, there are controversies about the composition (amlaki, haritaki and bibhitaki), preparation, and medicinal uses of Triphala.[5]

The active constituents are unknown. Triphala contains several compounds that have been proposed to be responsible for its claimed health benefits, including gallic acid, chebulagic acid, and chebulinic acid. [6][7]

Contemporary research on triphala

There is preliminary evidence that Triphala contains compounds with antioxidant properties in isolated cells and rats, however this has not yet been demonstrated in people.[6][8][9][10]

Triphala, widely used by natural Ayurvedic healers in India for thousands of years, contains 3 different fruits: Harada, Amla and Bihara.  The word “Triphala”literally means “three fruits”.  The combination of these three fruits cleanses the gastro-intestinal tract in a natural and gentle way.  Basically our “bathroom experience” becomes a better one  That is the best way I can put it!!

Why should we cleanse?

It’s always a good idea to cleanse! Get rid of toxins that build up in our bodies so that our bodies can function most efficiently and have that bright glowing skin we all crave and want!  More energy and feel less bloated!

And I’m not talking about cleansing with juicing or not eating.  No no, that’s a whole other conversation.  I absolutely believe in still eating a healthy diet while “cleansing”/taking Triphala.

I have suggested Triphala to many clients, students and friends and all of them have seen results.  You can call it a form of laxative if you’d like but this is totally safe and gentle on the body.  Yes, we are all different but seems like this one might be a miracle worker and work for everyone!

Suggested use: Take one pill before bedtime.  *Take on and off for a period of time OR once in a while when you feel you need it.  I usually take it when I feel I need a cleanse- about one or two times a week (usually when I have consumed a bigger meal or more food than usual).

Benefits of Triphala:

  • detoxify and cleanses the colon of toxins
  • removes excess fats
  • purifies the blood
  • removes toxins from the liver
  • reduces some forms of cholesterol (serum cholesterol)
  • reduces high blood pressure
  • high nutritional value: including high levels of vitamin C
  • high in antioxidants
  • strengthens hair roots and enriches hair color


The three fruits contained in Triphala are

Amalaki (Indian Gooseberry),

Haritaki (Indian Gallnut or Terminalia chebula),

and Bibhitaki (Beleric Myrobalan or Terminalia bellerica).

The prokinetic cleanser

An immensely popular Ayurvedic herbal formula,Triphala(Terminalia chebula,Terminalia bellirica and Emblica officinalis) is an effective bowel cleanser. It combines the goodness of Indian Gooseberry, Belleric Myrobalan and Chebulic Myrobalan, which work together to produce effective bowel movements.

The herbal compound provides overall support for digestion and helps ensure that the digestive tract works at optimal levels. Triphala relieves constipation and regularizes the digestive system, without disrupting the fluid-electrolyte balance in the body.

The herbs that make up Triphala are found in abundance in India.

Triphala, the well-known traditional Ayurvedic formulation, makes an excellent skin tonic. It is one of the most popular Ayurvedic medicinal herbs, prescribed by a number of Ayurvedic practitioners. Triphala literally means ‘three fruits’. The three fruits contained in Triphala are Amalaki (Indian Gooseberry), Haritaki (Indian Gallnut or Terminalia chebula), and Bibhitaki (Beleric Myrobalan or Terminalia bellerica). Since Triphala is tridoshic – equally balancing for Vata, Pitta and Kapha – it is beneficial for all skin types. Triphala nourishes the skin, both directly and indirectly. Amla (Indian gooseberry), one of the three ingredients in Triphala, is the richest known natural source of Vitamin C. Apart from the rich source of Vitamin C, Triphala also contains calcium – an important nutrient that helps enhance skin clarity and brings dull, tired skin to life.

Preparation Of Triphala Rasayana
Triphala Rasayana is usually prepared by mixing triphala with equal quantity of madhuka (mahua tree), tavakshir (East Indian arrowroot) pippali (long pepper), saindhava (long salt), and each one of the loha (iron), suvarna (gold), vacha (Acorus calamus) with either honey, ghee or sugar, in equal quantity.

Benefits Of Triphala
Triphala Rasayana is beneficial is promoting ojas, the finest product of digestion that prevents the occurrence of many diseases, creates luster and make the skin exude its natural glow and radiance.
It nourishes both the body and the mind, thereby promoting longevity of life. Therefore, Triphala Rasayana is very much beneficial for adults and children alike.
The Rasayana is especially beneficial for eyes. In case one has problems in eye sight, opting for Triphala Rasayana would be the best bet.
The Rasayana creates a balance in the cholesterol level, by removing ama from the fat tissue.
It helps in the purification of urinary tract, thereby helping the prevention of urinary tract diseases.
It also strengthens and cleanses the liver, which is one of its main functions. This ensures that the liver, one of the important parts of the body, stays healthy. It can also be said that the consumption of Rasayana prevents diseases related to the functioning of liver.
The medicine also helps the management of weight. Thus, it is beneficial for people, who want to loose weight.
It enhances the thirteen agnis (digestive fires), especially the main digestive fire in the stomach.
Triphala Rasayana is helpful in pacifying Kapha and Pitta. If taken on a regular basis, the Rasayana can be a powerful anti-aging medicine.
People suffering from skin inflammation, heat, infection, obesity will find the consumption of Triphala Rasayana as beneficial.
Diseases such as fatigue and anemia can be effectively cured by the regular consumption of Triphala Rasayana, if taken according to the prescribed doses.

  1.  Ayurvedic pharmacopoeia committee. The Ayurvedic Formulary of India, Part I, 2nd English ed. New Delhi: Controller of Publications; 2003
  2.  Anne McIntyre (7 September 2005). Herbal treatment of children: Western and Ayurvedic perspectives. Elsevier Health Sciences. pp. 278–. ISBN 9780750651745. Retrieved 24 July 2010.
  3.  Juss SS. Triphala – the wonder drug. Indian Med Gaz 1997;131:94-6.
  4.  Nadkarni AK. Indian Materia Medica. 3rd ed. Mumbai: Popular Press; 1976. p. 1308-15.
  5.  Harbans Singh Puri (2003). Rasayana: ayurvedic herbs for longevity and rejuvenation. CRC Press. pp. 30–. ISBN 9780415284899. Retrieved 24 July 2010.
  6.  Reddy TC, Aparoy P, Babu NK, Kalangi SK, Reddanna P (May 2010). “Kinetics and Docking Studies of a COX-2 Inhibitor Isolated from Terminalia bellerica Fruits”. Protein Pept LettPMID 20441561.
  7.  Pawar V, Lahorkar P, Anantha Narayana DB. Development of a RP-HPLC method for analysis of Triphala curna and its applicability to test variations in Triphala curna preparations. Indian J Pharm Sci [serial online] 2009 [cited 2010 Aug 1];71:382-6. Available from:
  8.  Mahesh R, Bhuvana S, Begum VM (August 2009). “Effect of Terminalia chebula aqueous extract on oxidative stress and antioxidant status in the liver and kidney of young and aged rats”. Cell Biochem. Funct. 27 (6): 358–63. doi:10.1002/cbf.1581PMID 19548245.
  9.  Sandhya T, Lathika KM, Pandey BN, et al. (October 2006). “Protection against radiation oxidative damage in mice by Triphala”. Mutat. Res. 609 (1): 17–25.doi:10.1016/j.mrgentox.2006.05.006PMID 16860592.
  10.  Srikumar R, Parthasarathy NJ, Manikandan S, Narayanan GS, Sheeladevi R (February 2006). “Effect of Triphala on oxidative stress and on cell-mediated immune response against noise stress in rats”. Mol. Cell. Biochem. 283 (1-2): 67–74. doi:10.1007/s11010-006-2271-0.PMID 16444587.


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