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DRUG APPROVALS BY DR ANTHONY MELVIN CRASTO .....FOR BLOG HOME CLICK HERE

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ORGANIC SPECTROSCOPY

Read all about Organic Spectroscopy on ORGANIC SPECTROSCOPY INTERNATIONAL 

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DR ANTHONY MELVIN CRASTO Ph.D

DR ANTHONY MELVIN CRASTO Ph.D

DR ANTHONY MELVIN CRASTO, Born in Mumbai in 1964 and graduated from Mumbai University, Completed his Ph.D from ICT, 1991,Matunga, Mumbai, India, in Organic Chemistry, The thesis topic was Synthesis of Novel Pyrethroid Analogues, Currently he is working with AFRICURE PHARMA, ROW2TECH, NIPER-G, Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Govt. of India as ADVISOR, earlier assignment was with GLENMARK LIFE SCIENCES LTD, as CONSUlTANT, Retired from GLENMARK in Jan2022 Research Centre as Principal Scientist, Process Research (bulk actives) at Mahape, Navi Mumbai, India. Total Industry exp 32 plus yrs, Prior to joining Glenmark, he has worked with major multinationals like Hoechst Marion Roussel, now Sanofi, Searle India Ltd, now RPG lifesciences, etc. He has worked with notable scientists like Dr K Nagarajan, Dr Ralph Stapel, Prof S Seshadri, etc, He did custom synthesis for major multinationals in his career like BASF, Novartis, Sanofi, etc., He has worked in Discovery, Natural products, Bulk drugs, Generics, Intermediates, Fine chemicals, Neutraceuticals, GMP, Scaleups, etc, he is now helping millions, has 9 million plus hits on Google on all Organic chemistry websites. His friends call him Open superstar worlddrugtracker. His New Drug Approvals, Green Chemistry International, All about drugs, Eurekamoments, Organic spectroscopy international, etc in organic chemistry are some most read blogs He has hands on experience in initiation and developing novel routes for drug molecules and implementation them on commercial scale over a 32 PLUS year tenure till date Feb 2023, Around 35 plus products in his career. He has good knowledge of IPM, GMP, Regulatory aspects, he has several International patents published worldwide . He has good proficiency in Technology transfer, Spectroscopy, Stereochemistry, Synthesis, Polymorphism etc., He suffered a paralytic stroke/ Acute Transverse mylitis in Dec 2007 and is 90 %Paralysed, He is bound to a wheelchair, this seems to have injected feul in him to help chemists all around the world, he is more active than before and is pushing boundaries, He has 100 million plus hits on Google, 2.5 lakh plus connections on all networking sites, 100 Lakh plus views on dozen plus blogs, 227 countries, 7 continents, He makes himself available to all, contact him on +91 9323115463, email amcrasto@gmail.com, Twitter, @amcrasto , He lives and will die for his family, 90% paralysis cannot kill his soul., Notably he has 38 lakh plus views on New Drug Approvals Blog in 227 countries......https://newdrugapprovals.wordpress.com/ , He appreciates the help he gets from one and all, Friends, Family, Glenmark, Readers, Wellwishers, Doctors, Drug authorities, His Contacts, Physiotherapist, etc He has total of 32 International and Indian awards

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How To Do A Liver Detox & Blood Cleanse – 5 Days


Lyranara.me's avatarLyra Nara Blog

By cleansing the liver, we’re talking about inducing the liver to purge all of the fats, old cholesterol deposits, gallstones, poisons, drug residues, and toxic waste stored therein. Probably nothing else you do (including even the colon detox) will make a greater difference in your overall health. The liver is so important to our well-being that many healers maintain that most diseases cannot develop in the body (that, in fact, no form of cell degeneration can occur) if the liver is functioning in an efficient, healthy manner. Conversely, an unhealthy liver is very likely at the root of most serious health problems.

By removing and eliminating toxins, then feeding your body with healthy nutrients, detoxifying can help protect you from disease and renew your ability to maintain optimum health. Specific foods will assist in boosting your metabolism, optimizing digestion, while allowing you to lose weight and fortify your immune system.

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Stopping the spread of breast cancer


Lyranara.me's avatarLyra Nara Blog

The primary cause of death from breast cancer is the spread of tumor cells from the breast to other organs in the body. Northwestern Medicine® scientists have discovered a new pathway that can stop breast cancer cells from spreading.

Working with human breast cancer cells and mouse models of breast cancer, scientists identified a new protein that plays a key role in reprogramming cancer cells to migrate and invade other organs. When that protein is removed from cancer cells in mice, the ability of the cells to metastasize to the lung is dramatically decreased.

The protein, hnRNPM, helps launch a cascade of events that enables breast cancer cells to break away from the original tumor, penetrate the blood stream, invade another part of the body and form a new nodule of that tumor.

“Our research suggests that hnRNPM could be an effective target to stop cancer cells from spreading,” said…

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Allergy Test Could Spot Unexpected Milk Allergens Medical Diagnostics: Test can identify both common and unfamiliar milk allergens for a patient


20140624lnj1-milkallergy

Milk Allergen Tracker
Researchers run an allergic patient’s blood serum (top row) past a column of magnetic beads (orange circles) dotted with antibodies (black Y-shapes) that bind human immunoglobulin E (IgE) antibodies. The scientists next chemically crosslink any bound IgE antibodies (red Y-shapes) to the beads, then expose the now-personalized IgE-bound column to milk (bottom row). Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) identifies the mass and helps predict the structure of both familiar and unfamiliar bound milk allergens.
Credit: Natalia Gasilova

Plant flavonoid luteolin blocks cell signaling pathways in colon cancer cells


Ralph Turchiano's avatarCLINICALNEWS.ORG

30 Jan 2012

Luteolin is a flavonoid commonly found in fruit and vegetables. This compound has been shown in laboratory conditions to have anti-inflammatory, anti-oxidant and anti-cancer properties but results from epidemiological studies have been less certain. New research published in BioMed Central’s open access journal BMC Gastroenterology shows that luteolin is able to inhibit the activity of cell signaling pathways (IGF and PI3K) important for the growth of cancer in colon cancer cells.

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Epilogue: Envisioning New Insights in Cancer Translational Biology


Summary of Translational Medicine – Cardiovascular Diseases – Part 1


Prologue to Cancer – ebook 4 – Where are we in this journey?


Study Finds Shu Gan Liang Xue Herbal Formula Has Breast Cancer Anti Tumor Effect


Lyranara.me's avatarLyra Nara Blog

There are a host of herbal formulas that show anti tumor properties for various cancers in clinical studies.  Chinese researchers publishing in the Journal of Ethnopharmacology recently conducted a study looking at the effect of Shu Gan Liang Xue Formula on breast cancer tumors – particularly estrogen receptor positive breast cancer line ZR-75-1.  Researchers investigated these anti-tumor functions in vitro and in vivo.

Shu Gan Liang Xue is a traditional Chinese herbal formula, it is comprised of the following herbs:

  • Chai Hu
  • Bai Shao
  • Wu Wei Zi
  • Dan Pi
  • Bai Wei
  • Zi Cao

Researchers understand that estrogen is a driver behind breast cancer.  Two other substances, aromatase and steroid sulfatase are enzymes which contribute to estrogen synthesis.  The researchers found that Shu Gan Liang Xue inhibits aromatase and steriod sulfatase which decreases their expression and their effect of estrogen synthesis.  They found this both in vitro and in vivo.

In addition to…

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Too-clean homes may encourage child allergies, asthma


atasteofcreole's avatarAtasteofcreole's Blog

http://www.live5news.com/story/25711359/too-clean-homes-may-encourage-child-allergies-asthma-study

(HealthDay News) — Cleanliness may be next to godliness, but a home that’s too clean can leave a newborn child vulnerable to allergies and asthma later in life, a new study reports.

Infants are much less likely to suffer from allergies or wheezing if they are exposed to household bacteria and allergens from rodents, roaches and cats during their first year of life, the study found.

The results stunned researchers, who had been following up on earlier studies that found an increased risk of asthma among inner-city dwellers exposed to high levels of roach, mouse and pet droppings and allergens.

“What we found was somewhat surprising and somewhat contradictory to our original predictions,” said study co-author Dr. Robert Wood, chief of the Division of Allergy and Immunology at the Johns Hopkins Children’s Center in Baltimore. “It turned out to be completely opposite — the more of those three allergens…

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Odor Code for Food Based on a Few Volatile Substances


thumbnail image: Follow Your Nose

 

The actual flavor of a food is experienced through our sense of smell rather than with our tongue. However, of the large number of volatile compounds in foods, only about 230 are involved in the scent, as reported by German scientists in the journal Angewandte Chemie. The different smells derive from characteristic combinations of three to forty of these odorants.

http://www.chemistryviews.org/details/ezine/6323291/Follow_Your_Nose.html?utm_source=dlvr.it&utm_medium=facebook