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ORGANIC SPECTROSCOPY

Read all about Organic Spectroscopy on ORGANIC SPECTROSCOPY INTERNATIONAL 

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DR ANTHONY MELVIN CRASTO Ph.D

DR ANTHONY MELVIN CRASTO Ph.D

DR ANTHONY MELVIN CRASTO, Born in Mumbai in 1964 and graduated from Mumbai University, Completed his Ph.D from ICT, 1991,Matunga, Mumbai, India, in Organic Chemistry, The thesis topic was Synthesis of Novel Pyrethroid Analogues, Currently he is working with GLENMARK PHARMACEUTICALS LTD, Research Centre as Principal Scientist, Process Research (bulk actives) at Mahape, Navi Mumbai, India. Total Industry exp 30 plus yrs, Prior to joining Glenmark, he has worked with major multinationals like Hoechst Marion Roussel, now Sanofi, Searle India Ltd, now RPG lifesciences, etc. He has worked with notable scientists like Dr K Nagarajan, Dr Ralph Stapel, Prof S Seshadri, Dr T.V. Radhakrishnan and Dr B. K. Kulkarni, etc, He did custom synthesis for major multinationals in his career like BASF, Novartis, Sanofi, etc., He has worked in Discovery, Natural products, Bulk drugs, Generics, Intermediates, Fine chemicals, Neutraceuticals, GMP, Scaleups, etc, he is now helping millions, has 9 million plus hits on Google on all Organic chemistry websites. His friends call him Open superstar worlddrugtracker. His New Drug Approvals, Green Chemistry International, All about drugs, Eurekamoments, Organic spectroscopy international, etc in organic chemistry are some most read blogs He has hands on experience in initiation and developing novel routes for drug molecules and implementation them on commercial scale over a 30 year tenure till date Dec 2017, Around 35 plus products in his career. He has good knowledge of IPM, GMP, Regulatory aspects, he has several International patents published worldwide . He has good proficiency in Technology transfer, Spectroscopy, Stereochemistry, Synthesis, Polymorphism etc., He suffered a paralytic stroke/ Acute Transverse mylitis in Dec 2007 and is 90 %Paralysed, He is bound to a wheelchair, this seems to have injected feul in him to help chemists all around the world, he is more active than before and is pushing boundaries, He has 9 million plus hits on Google, 2.5 lakh plus connections on all networking sites, 50 Lakh plus views on dozen plus blogs, He makes himself available to all, contact him on +91 9323115463, email amcrasto@gmail.com, Twitter, @amcrasto , He lives and will die for his family, 90% paralysis cannot kill his soul., Notably he has 19 lakh plus views on New Drug Approvals Blog in 216 countries......https://newdrugapprovals.wordpress.com/ , He appreciates the help he gets from one and all, Friends, Family, Glenmark, Readers, Wellwishers, Doctors, Drug authorities, His Contacts, Physiotherapist, etc

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Dr Anthony’s New Drug Approvals hits 13 lakh views in 212 countries


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Dr Anthony’s New Drug Approvals hits 13 lakh views in 212 countries

An Indian helping millions

9e3e7-new-india-map

MAKING INDIANS FEEL PROUD

LINK

https://newdrugapprovals.org/

 

////////blog, Dr Anthony , New Drug Approvals,  13 lakh views, 212 countries, India

 

Flow Chemistry Symposium & Workshop 16-17 June at IICT, Hyderabad, India


STR1

MESSAGE FROM VIJAY KIRPALANI

2-day FLOW CHEMISTRY Symposium + Workshop has been organized on 16-17 June 2016 at

IICT Hyderabad, India   by Flow Chemistry Society – India Chapter (in collaboration with IICT-Hyderabad & IIT-B)

with speakers from India, UK, Netherlands and Hungary.

Both days have intensive interactive sessions on the theory and industrial applications of Flow Chemistry followed by live demonstrations using 7 different Flow Reactor platforms — from microliters to 10,000 L/day industrial scale.

The Fees are Rs. 5,000 for Industry Delegates and Rs. 2,500 for Academic Delegates (+15% Service Tax) : contact : vk@pi-inc.co or msingh@cipla.com

I have attached a detailed program and look forward to meeting you at the event..

STR1

Vijay Kirpalani

Best regards

Vijay Kirpalani
President
Flow Chemistry Society – India Chapter
email : vk@pi-inc.co
Tel: +91-9321342022 // +91-9821342022

ABOUT

IICT, Hyderabad, India

Dr. S. Chandrasekhar,
Director

CSIR-Indian Institute of Chemical Technology (IICT)

Hyderabad, India

SPEAKERS

Vijay Kirpalani

Mr Vijay Kirpalani

President
Flow Chemistry Society – India Chapter, INDIA

Charlotte Wiles

Dr Charlotte Wiles , CHEMTRIX

UK &THE NETHERLANDS,UNIV OF HULL

 

 

Prof. Anil Kumar

Prof Anil Kumar( IIT-B), INDIA

 

Manjinder Singh

/////Flow Chemistry, Symposium,  Workshop,  16-17 June, IICT, Hyderabad, India

HELP, Need one time help to pay 10 year concessional subscription to this, your favorite blog to WordPress


Just One viewer please come forward

Dear Kind Viewer’s

WordPress is kind to me and negotiated a one time 10 year concessional subscription of 260 US dollars…….https://newdrugapprovals.org/

I need one time help to pay this one time 10 year concessional subscription to our favorite blog.

This is done to keep this blog running even after my death.

Currently I am paying 99 US Dollars per annum

email me

amcrasto@gmail.com

call +919323115463

Paypal will work for me via email request to you by me, Indian govt does not allow automatic transfer via paypal buttons on the blog.

email me at amcrasto@gmail.com and tell me amount,  i will request you  via paypal

Anthony Melvin Crasto Ph.D

DR ANTHONY CRASTO

LIONEL MY SON, MY MOTIVATION

.

He was only in first standard in school when I was hit by a deadly one in a million spine stroke called acute transverse mylitis, it made me 90% paralysed and bound to a wheel chair, He cried bitterly and we had never seen him so depressed

Now I keep Lionel as my source of inspiration and helping millions, thanks to millions of my readers who keep me going and help me to keep my son and family  happy.

ps

The views expressed are my personal and in no-way suggest the views of the professional body or the company that I represent,

///////////

 

 

 

 

 

DRUG APPROVALS BY DR ANTHONY MELVIN CRASTO …..FOR BLOG HOME CLICK HERE

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P.S

 

THE VIEWS EXPRESSED ARE MY PERSONAL AND IN NO-WAY SUGGEST THE VIEWS OF THE PROFESSIONAL BODY OR THE COMPANY THAT I REPRESENT, amcrasto@gmail.com, +91 9323115463 India.

DISCLAIMER

I , Dr A.M.Crasto is writing this blog to share the knowledge/views, after reading Scientific Journals/Articles/News Articles/Wikipedia. My views/comments are based on the results /conclusions by the authors(researchers). I do mention either the link or reference of the article(s) in my blog and hope those interested can read for details. I am briefly summarising the remarks or conclusions of the authors (researchers). If one believe that their intellectual property right /copyright is infringed by any content on this blog, please contact or leave message at below email address amcrasto@gmail.com. It will be removed ASAP

HELP, Need one time help to pay 10 year concessional subscription to this, your favorite blog to WordPress


 

Just One viewer please come forward

 

Dear Kind Viewer’s

WordPress is kind to me and negotiated a one time 10 year concessional subscription of 260 US dollars…….https://newdrugapprovals.org/

I need one time help to pay this one time 10 year concessional subscription to our favorite blog.

This is done to keep this blog running even after my death.

Currently I am paying 99 US Dollars per annum

email me

amcrasto@gmail.com

call +919323115463

Paypal will work for me via email request to you by me, Indian govt does not allow automatic transfer via paypal buttons on the blog

email me at amcrasto@gmail.com and tell me amount,  i will request you  via paypal

Anthony Melvin Crasto Ph.D

DR ANTHONY CRASTO

 

LIONEL MY SON, MY MOTIVATION

.

 

He was only in first standard in school when I was hit by a deadly one in a million spine stroke called acute transverse mylitis, it made me 90% paralysed and bound to a wheel chair, He cried bitterly and we had never seen him so depressed

Now I keep Lionel as my source of inspiration and helping millions, thanks to millions of my readers who keep me going and help me to keep my son and family  happy.

ps

The views expressed are my personal and in no-way suggest the views of the professional body or the company that I represent,

 

///////////

New Drug Approvals Blog has 2 lakh plus viewers in USA alone


flags_1

New Drug Approvals Blog has 2 lakh plus viewers in USA alone

that is 200 thousand viewers

A record 1170135 views (11 lakh plus)all over the world in 211 countries

that is 1100 thousand plus views on this blog

I suffered a paralytic stroke in dec 2007 and bound to a wheelchair, this seems to have injected feul in me to help chemists around the world, I am more active than before and  pushing boundaries, I have 2,5 lakh connections on all networking sites, I am available to all, contact me on +91 9323115463, amcrasto@gmail.com, Twitter @amcrasto

 

 

 

My son lionel was only in first standard in school when I was hit by a deadly one in a million spine stroke called acute transverse mylitis, it made me 90% paralysed and bound to a wheel chair, He cried bitterly and we had never seen him so depressed

Now I keep Lionel as my source of inspiration and helping millions, thanks to millions of my readers who keep me going and help me to keep my son and family happy.

success

 

////////////

New Drug Approvals blog by Dr Anthony Crasto hits ten lakh views in 211 countries


 

flags_1

New Drug Approvals hits ten lakh views in 211 countries

https://newdrugapprovals.org/

 

 

 

 

ANTHONY MELVIN CRASTO

THANKS AND REGARD’S
DR ANTHONY MELVIN CRASTO Ph.D

amcrasto@gmail.com

MOBILE-+91 9323115463
GLENMARK SCIENTIST ,  INDIA
web link
shark

 

photo
Dr. Anthony Melvin Crasto
Principal Scientist, Glenmark Pharma
    

 

 

//////////

This blog New Drug Approvals will touch 10 lakh views soon……..as on 7 NOV 2015


nda nov 2015

This blog New Drug Approvals will touch 10 lakh views soon……..as on 7 NOV 2015

https://newdrugapprovals.org/

 

 

 

////////

Dr. Ashok Kumar, President – Research and Development (Chemical) at IPCA LABORATORIES LTD


Dr. Ashok Kumar

PRESIDENT – R&D (Chemical) at IPCA LABORATORIES LTD
LINKS
 Intro

The 25-year process patent regime allowed a large number of generic companies in India to reap rich dividends, but there were few who believed in the need to go beyond the horizon of process development to tap into unexplored terrains.

In the year 2000, when Dr Ashok Kumar joined the board of Mumbai-based IPCA Labs, he was determined to implement a different strategy to accelerate IPCA’s R&D initiatives. Having seen IPCA grow from a 350-crore company to one clocking an annual turnover of over 2,500 crore, Dr Ashok Kumar, president- Center for Research and Development, IPCA Labs, is now leaving no stone unturned to exploit the biotech and drug discovery space.

 Dr. Ashok Kumar

Dr Kumar completed his M Sc in Chemistry from Kumaun University, now in Uttarakhand. He then decided to pursue his PhD in organic chemistry and joined Banaras Hindu University (BHU), but opted out three months later to do PhD from the Central Drug Research Institute (CDRI), Lucknow, under the guidance of the then director of the CDRI, Dr Nityanand.

Dr Kumar did his post doctoral studies from the University of Sussex, UK. “During the 1980s, jobs in scientific research were not available in India. It was always good to go for higher studies abroad,” he says about the reason for going abroad. “Dr Nityanand taught me to be explorative and think of new ways to approach a subject. I still follow that process,” he says. In 1984, Dr Kumar decided to return to India and took up a job at the Imperial Chemical Laboratories (ICI), Mumbai. In 1994, he joined Lupin Labs where he was once again involved in process development of small molecules.

In 2000, he joined IPCA Labs where he immediately focused on bringing about two changes – introducing a library and bringing in systems like a nuclear magnetic resonance (NMR), which at that time was the costliest instrument. “I understood the importance of high-end technologies since my PhD years at the CDRI (which housed a couple of NMRs) and then in the UK. You do not enjoy organic chemistry without an NMR. My main objective at IPCA was cost reduction along with process development.”

In the last few years, IPCA’s R&D team has brought out over 100 products. Under Dr Kumar, IPCA has an R&D center in Mumbai and another parallel R&D center in Ratlam, Madhya Pradesh. “In Mumbai, we have around 60 people. The Mumbai team takes care of basic chemistry and small-scale development. Scaling up is done in Ratlam,” he explains. IPCA is also coming up with a facility at Vadodara, Gujarat, that will look into large-scale manufacture of both organic and biotech drugs. The facility will have a strategic importance for the company. “We are growing at a rate of 20 per cent year-on-year and, next year, we intend to add 500 crore to our revenue. For that, we need more products to come to the market and more volume,” he adds.

Apart from organic chemistry, Dr Kumar is currently aligning his attention to two promising but high risk segments – fermentation-based products and biosimilars. “We are working on five-to-six molecules, mainly active metabolites that are intermediates or biotech drugs,” he adds. IPCA has also collaborated with two companies in India for the development of biosimilars. Currently, there are three biosimilar products in the pipeline.

The R&D team at IPCA ventured into drug discovery three years ago. It has two products in the pipeline; one anti-malarial and the other anti-thrombotic. “We will be filing the investigational new drug application for one molecule this year and for the other next year. The success rate here is 99 per cent,” adds Dr Kumar. IPCA has also joined hands with the CDRI and licensed two molecules in the anti-malarial space. One of these molecules is currently in phase-I stage.

Innogen summit India 2016, 18-19 Aug, Mumbai, India, HOTEL HOLIDAY INN, Mumbai International Airport,Organised by Inventicon Business Intelligence Pvt. Ltd………topic is Supergenerics, Innovation in Generics, commercialization, regulatory, other insights,

A0a1

Dr. Ashok Kumar, President – Centre for Research & Development, Ipca Laboratories Ltd, at Innogen summit India 2016, 18-19 Aug, Mumbai, India,, HOTEL HOLIDAY INN, Mumbai International Airport,Organised by Inventicon Business Intelligence Pvt. Ltd — with DR ASHOK KUMAR OF IPCA at Holiday Inn-Mumbai Intl Airport.

 

A2

PANEL DISCUSSION, Dr. Ashok Kumar, President – Centre for Research & Development, Ipca Laboratories Ltd , Dr. Nilima A. Kshirsagar, National Chair Clinical Pharmacology, ICMR Government of India, Yugal Sikri, Chairman – Pharmaceutical Management, School of Business Management, SVKM’s Narsee Monjee Institute of Management Studies — with Yugal Sikri,, Nilima A. Kshirsagarand ASHOK KUMAR OF IPCA at Holiday Inn-Mumbai Intl Airport.

JOURNEY

2005…..PRESIDENT
In 2000, he joined IPCA Labs
1994, he joined Lupin Labs where he was once again involved in process development of small molecules.
1984 Dr Kumar decided to return to India and took up a job at the Imperial Chemical Laboratories (ICI), Mumbai.
Dr Kumar did his post doctoral studies from the University of Sussex, UK.
PhD in organic chemistry and joined Banaras Hindu University (BHU), but opted out three months later to do PhD from the Central Drug Research Institute (CDRI), Lucknow, under the guidance of the then director of the CDRI, Dr Nityanand.
Dr Kumar completed his M Sc in Chemistry from Kumaun University, now in Uttarakhand
 
 DR NITYANAND
 DIRECTOR, CDRI, LUCKNOW, INDIA
img_Inanim01.jpg
img_pgene01.jpg

Experience

PRESIDENT – R&D

IPCA LABORATORIES LTD

2005 – Present (10 years)

Patent 1

chlorthalidone is 3-hydroxy-3-(3′-sulfamyI-4′- chlorophenyl)phtalimidine and is represented by the structural formula shown below.

Figure imgf000002_0001
Figure imgf000004_0001

Chlorthalidone Formula 1

(Scheme 2). The starting material, 2-(4′-chlorobenzoyl) benzoic acid, of Formula (2) and its preparation was reported earlier for example in patents US 4500636, US 30555904, US4379092, US 3764664.

Figure imgf000008_0002
Figure imgf000008_0001

Formula 9 CIS03H

Figure imgf000008_0003
Figure imgf000008_0004

Chlorthalidone Formula 10 Formula 1

Figure imgf000008_0005

 PATENT 2

 https://www.google.co.in/patents/US7847094Quetiapine and its process for preparation is first disclosed in the patent specification EP0240228 and various other processes for the preparation are disclosed in EP0282236, WO0155125, WO9906381, WO2004076431.

Figure US07847094-20101207-C00001

 PATENT 3

http://www.google.com/patents/US20080009635

  . The chemical name of Ondansetron is 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl)-1H-imidazole-1-yl)methyl]-4H-carbazol-4-one and is represented by the structural formula given below:

Figure US20080009635A1-20080110-C00001

PATENT 4

  • scheme 2.
  • Figure US20100081847A1-20100401-C00002
 
 AT A SEMIMAR
Map of ipca

Chemical Research & Development Centre

123-AB, Kandivli Industrial Estate, Kandivli (West)
Mumbai 400 067, Maharashtra

icon_phone.jpg+91 (22) 6647 4755 / 56
icon_fax.jpg+91 (22) 6647 4757
Kumaun University
 Imperial Chemical Laboratories (ICI), Mumbai
/////Dr. Ashok Kumar, PRESIDENT, R&D, IPCA LABORATORIES LTD

ORGANIC SPECTROSCOPY INTERNATIONAL HAS 2 LAKH VIEWS


ORGANIC SPECTROSCOPY INTERNATIONAL HAS 2 LAKH VIEWS

Read by one and all in academics and industry

link is ……http://orgspectroscopyint.blogspot.in/

I get minimum 1000 hits in a day and all across the world

 

 

सुकून उतना ही देना प्रभू, जितने से जिंदगी चल जाये।औकात बस इतनी देना,कि औरों का भला हो जाये।………..P.S. : The views expressed are my personal and in no-way suggest the views of the professional body or the company that I represent.

 

सुकून उतना ही देना प्रभू, जितने से जिंदगी चल जाये। औकात बस इतनी देना, कि औरों का भला हो जाये।
DRUG APPROVALS BY DR ANTHONY MELVIN CRASTO …..FOR BLOG HOME CLICK HERE

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09b37-misc2b027LIONEL MY SON
He was only in first standard in school when I was hit by a deadly one in a million spine stroke called acute transverse mylitis, it made me 90% paralysed and bound to a wheel chair, Now I keep him as my source of inspiration and helping millions, thanks to millions of my readers who keep me going and help me to keep my son happy
सुकून उतना ही देना प्रभू, जितने से
जिंदगी चल जाये।
औकात बस इतनी देना,
कि औरों का भला हो जाये।

 

New Drug Approvals blog fast approaching 8 lakh views ( 27/7/2015)


Flag CounterNew Drug Approvals blog fast approaching 8 lakh views ( 27/7/2015)

799174 VIEWS IN 208 COUNTRIES

 

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