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FDA Accepts Endo’s Aveed Application
Endo Health Solutions said that regulators accepted for review new data for its long-acting testosterone injection Aveed and will make a ruling on the drug by Feb. 28. The Food and Drug Administration asked Endo for more information in May.
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Welcome to Bioinfomedical.com

http://www.bioinfomedical.com/index.php
Prof. Dr. Rafael Boritzer
P.O.Box 88355, Honolulu, Hawaii 96830 U.S.A.
http://www.bioinfomedical.com/index.php
we are marketers of non-branded recombinant proteins with a primary mission of high quality, low priced material for encouraging biopharma research and development outside of North America. We try to integrate our supply services with education of our clients’ with industry videos and information.
Welcome to Bioinfomedical.com
BioInfoMedical was established in 1989 by a team of experienced medical specialists, world-known scientists and marketing professionals. The company has two operating divisions:
InfoMedical Biotechnology and InfoMedical Consulting.
InfoMedical Biotechnology provides products and services used in gene, protein and cell research, drug discovery and development, as well as in biopharmaceutical manufacturing.
InfoMedical Consulting assists companies in strategic market expansion, industry research, environmental analysis, and developing successful market plans for worldwide business-winners.
We are proud to serve our customers around the globe. Our clients are: academic research institutions, biotechnology and pharmaceutical companies, medical research centers, hospitals, reference laboratories, agricultural and chemical companies, as well as leading private and governmental business organizations.
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see a video of DR RAFI
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Cytokines
- Adiponectin
- Angiopoietin
- Apoliprotein
- B-Cell Activating Factor
- Beta Defensin
- Bone Morphogenetic Protein
- B type Natriuretic Peptide
- Endoglin
- Flt3 Ligand
- Hedgehog Protein
- Interleukin
- Interferon
- Leukemia Inhibitory Factor
- Resistin
- Thrombopoietin
- Trefoil Factor
- Tumor Necrosis Factor
- Visfatin
- Other
- EBI3
- Serum Amyloid A
- Betacellulin
- Follistatin
Growth Factors
- Colony Stimulating Factor
- CTGF
- Epidermal Growth Factor
- Erythropoietin
- Fibroblast Growth Factor
- Galectin
- Growth Hormone
- Hepatocyte Growth Factor
- IGFBP
- Insulin-Like Growth Factor
- Insulin
- Keratinocyte Growth Factor
- Leptin
- Macrophage Migration Inhibitory Factor
- Melanoma Inhibitory Activity
- Myostatin
- Noggin
- Osteoprotegerin
- PDGF
- Placental Lactogen
- Prolactin
- RANK Ligand
- Stem Cell Factor
- Transforming Growth Factor
- VEGF
- Other
- Activin-A
- Retinol Binding Protein
- Omentin
- Oncostatin-M
Chemokines
- Eotaxin
- GRO
- Interleukin-8 (CXCL8)
- IP-10 (CXCL10)
- I-TAC (CXCL11)
- Lymphotactin (XCL1)
- MCP
- MDC (CCL22)
- MEC (CCL28)
- MIG (CXCL9)
- MIP
- Platelet Factor-4 (CXCL4)
- Rantes (CCL5)
- SDF (CXCL12)
- TARC (CCL17)
- Other
- ENA 78
- NAP-2 (CXCL7)
CD Antigens
Neurotrophins
- Beta-Nerve Growth Factor
- Ciliary-Neurotrophic Factor
- Glia Maturation Factor
- Pigment Epithelium-Derived Factor
- Other
Hormones
- Endothelin
- Exendin
- FSH
- GHRP
- GLP
- Glucagon
- HCG
- Inhibin A
- LHRH
- Peptide Hormones
- PTH
- Stanniocalcin
- Thymosin
- Thyrostimulin
- TSH
- Other
Enzymes
- 14-3-3
- Adenylate Kinase
- Carbonic Anhydrase
- Casein Kinase-2
- Creatin Kinases
- Cyclophilin
- Deaminase
- Dehydrogenase
- DNA Polymerase
- EGF Receptor
- Enteropeptidase/Enterokinase
- FGF Receptors
- FK506 Binding Protein
- Gluteradoxin
- Hexokinase
- Isomerase
- Kallikrein
- LYVE1
- Matrix Metalloproteinase
- Natural Enzymes
- Neuron Specific Enolase
- Oxidase
- Paraoxonase
- Peptidase
- Peroxiredoxin
- Phosphatase
- Phosphoinositide 3-kinase
- Phosphorylase
- Proteasome
- Protein Kinase-A
- Protein Kinase-C
- Protein Kinases
- Reductase
- Secreted Phospholipase A2
- Synthase
- Synthetase
- TIE1,TIE2
- Transferase
- Tyrosine Kinase
- Ubiquitin Conjugating Enzyme
- VEGF Receptors
- Other
- Mutase
- Mitogen-Activated Protein Kinase
- Hydroxylase
- Hydrolase
- Hydratase
- Glycosylase
- Lipase
- Esterase
- Epimerase
- Decarboxylase
- Nuclease
- Nudix Type Motif
- Oxygenase
- Activating Transcrition Factor
- Aldolase
- Aurora Kinase
- Calcium and Integrin Binding
- Cyclin
- Cyclin-Dependent Kinase
- Endonuclease
- Enolase
- Jun N-terminal Kinase
- Jun Proto-Oncogene
- Lyase
- Nucleotidase
- Peroxisome Proliferator Activated Receptor
- Polymerase
- Protein Kinase Akt1/PKB alpha
Viral Antigens
- Borrelia
- Chagas
- Chlamydia
- Cytomegalo
- Dengue
- EBV
- Encephalitis
- HBsAg
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis D
- Hepatitis E
- Herpes
- HIV
- HTLV
- Influenza
- Malaria
- Measles
- Rubella
- SARS
- Toxoplasma
- Treponema
- West Nile
- Varicella
- Papillomavirus
- Mycoplasma
- Hantavirus
- Parvovirus
Recombinant Proteins
- Albumin
- Allergy
- Annexin
- Beta 2 Microglobulin
- B Cell Lymphoma
- BID
- Calbindin
- Calmodulin
- Cardiac Troponin
- Cell Division Cycle
- Chromogranin
- Collagen
- Complement Component
- Cytokeratin
- Cystatin
- Eukaryotic Translation Initiation Factor
- FABP
- Ferritin
- Heat Shock Protein
- High-Mobility Group
- Killer Cell
- Member RAS Oncogene Family
- Myelin Oligodendrocyte Glycoprotein
- Myosin Light Chain
- p53
- PCNA
- Profilin
- Programmed Cell Death
- Protein-A, A/G & G
- Regenerating Islet-Derived
- Secretagogin
- Selectin
- Serpin
- SMAD
- Streptavidin
- Superoxide Dismutase
- Synaptobrevin
- Synaptosomal Associated Protein
- Synuclein
- SRY (Sex Determining Region Y)-Box
- Stathmin
- Thioredoxin
- TNF receptor-Associated Factor
- Trypsin
- Vimentin
- Other
- Visinin-Like Protein
- Ubiquitin
- Syndecan
- Sirtuin
- Regulator of G-Protein Signaling
- Ras-Related C3 Botulinum Toxin Substrate
- Outer Membrane Protein
- Non-Metastatic Cells
- Myoglobin
- Microtubule-Associated Protein
- Melanoma Antigen Family A
- Hypoxia-Inducible Factor
- DNA-Damage Protein
- Endoplasmic Reticulum Protein
- Chromosome Open Reading Frame
- Calcium Binding Protein
- ADP-Ribosylation Factor
- Small Nuclear Ribonucleoprotein Polypeptide
- Calcium Binding Protein
- Centromere Protein
- Chloride Intracellular Channel
- Chromatin Modifying Protein
- Chromobox
- Coagulation Factors
- C-Reactive Protein
- Crystallin
- Cytochrome
- Dynein Light Chain
- Ephrin
- Exosome Component
- NANOG
- Reticulocalbin
- Ribosomal Protein
- Septin
- Transgelin
- Tropomyosin
- U6 Small Nuclear RNA
- Vacuolar Protein Sorting
- Fibronectin
Natural Proteins
Monoclonal Antibodies
- Anti Human Cytokine
- Anti Human Lymphocyte
- Anti Mouse Cytokine
- Anti Human Chemokine
- Anti Human Enzyme
- Anti Human Heat Shock Protein
- Anti Mouse Lymphocyte
- Anti-GST
- Anti Viral
- Other
Polyclonal Antibodies
Test Category New
http://www.bioinfomedical.com/index.php

A Return to Health
One Woman’s Ayurvedic Experience
by Jodi Boone
Over a cup of tea, she told me how they found her tumour. Mira, a middle-aged woman with large blue eyes and a gentle smile, holds a Ph.D. in Organizational Development and works as an administrator for the Swedish Army.
She explained how the stress and long hours of her work had culminated in 25 kilos of extra weight and high blood pressure. “For 20 years, I didn’t have time for myself – no time for exercise and no energy to shop or cook meals at home,” Mira said. Devoted to her studies in her 20’s and later to her career, Mira acknowledged that her trip to India in 2010 was the first time in her life she’d taken to focus on her health.
“I’d never been to India before, and I’d never heard of Ayurveda,” said Mira. One evening, as she searched…
View original post 955 more words
Fruit Lowers the Risk of Diabetes
The press is all over a recent study done at the Harvard school of public health that was published in the British Medical Journal last week. The study showed that those that ate fruit had a lower risk of diabetes. Specifically they singled out blueberries for a 25% reduction in risk. Grapes offered 11%, apples 5%, prunes 11%, pears 7%. This was not a randomized trial so there are a lot of uncontrolled variables but that being said they did look at 187,382 patients so that sample size does give this study a lot of weight. It also brings further support to a recommendation I have been giving to my diabetic or pre-diabetic patients for years, become a vegan and forget about the ADA (American Diabetes Association) diet.
A study done in 2006 published in Diabetes Care compared patients on a Vegan diet to patients on the ADA diet. The Vegan diet patients…
View original post 311 more words
The Claimed Intermediate database by Tcipatent Ltd

Eddie Kehoe
Principal & Technical Director at Tcipatent Ltd
Hove, Brighton and Hove, United KingdomPharmaceuticalsThe Claimed Intermediate – a Structure Searchable Process Patent Database for Marketed Pharmaceutical Drugs (INNs).
Patent examining, searching, analysis and abstracting especially in the Chemical subject area.
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The Claimed Intermediate is an online database
which covers Process Patents for Named Marketed Pharmaceutical Drugs – whether intermediates are claimed or not – for a low-cost subscription.
- Structure Searchable
- Includes INNs in at least one major Market
- Includes Drug Synthesis often buried in a Plethora of Patents
- Informs Pipeline decisions
- Provides targeted Patent data in a Visual form
- Informs Commercial Synthesis profitability

shared message from Eddie Kehoe
If anybody would like a trial of the database they could contact either myself eddie.kehoe@tcipatent.com, or my wife and fellow director, Pat Kehoe (pat.kehoe@tcipatent.com).
Here are temporary logons , please request trial
(deactivated automatically in five working days):
Link: Link: www.tcipatent.com/tcidb/
Structure Searchable Patent Database for Processes covering Named Marketed Pharmaceutical Drugs (INNs). The database is an ongoing Watching Service combined with a Backward Drug Service.
Eddie Kehoe
Principal & Technical Director
Tcipatent Ltd
www.tcipatent.com
info@tcipatent.om
tcipatent.com
Office: +44 (0)1273 736080
43 Farm Road, Hove, BN3 1FD, United Kingdom
Eddie Kehoe:
eddie.kehoe@tcipatent.com
Mobile – 07425629637
Skype – eddieskihoe
TWITTER-TCIPATENT
Pat Kehoe:
pat.kehoe@tcipatent.com
Mobile – 07585295531
Skype – patkehoe170348

Database Updates:
Recently Added Records
| Aliskiren | Ambrisentan |
| Asenapine | Atorvastatin |
| Bosentan | Cabazitaxel |
| Cefamandole | Dasatinib |
| Desogestrel | Dexmedetomidine |
| Docetaxel | Doripenem |
| Doxapram | Duloxetine |
| Etonogestrel | Etoricoxib |
| Etravirine | Fluvastatin |
| Gefitinib | Iodixanol |
| Iohexol | Iopamidol |
| Linagliptin | Mitiglinide |
| Montelukast | Moxonidine |
| Oseltamivir | Paclitaxel |
| Perampanel | Pitavastatin |
| Pravastatin | Praziquantel |
| Ritodrine | Rosuvastatin |
| Silodosin | Sitagliptin |
| Ticagrelor | Ulipristal |
| Zidovudine |
………..

photo
Coopers Cask – Pub in Hove BN3 1FB
Eddie is closeby
HOME REMEDIES FOR CHOLESTEROL

Home Remedies for Cholesterol: Onions contain high levels of quercetin, an important flavonoid that reduces cholesterol. high concentrations of the compound quercetin hinderS the oxidation process of LDL, or “bad,” cholesterol, which help prevent the negative effects of this type of cholesterol.
===> http://www.askveda.in/ – Ayurveda health-tips, home remedies & expert advice
Antibody lipid treatments enter final furlong
A tiny pain-free jab every two weeks could be the future of cholesterol-lowering for high-risk patients, according to clinical researchers gathered in Amsterdam for the European Society of Cardiology congress.
Eli Roth at the University of Cincinnati said that two companies are currently neck and neck in the race to bring the first PCSK9 antibody to market. Partners Sanofi and Regeneron may have the edge, with Phase III data on their fully human monoclonal antibody alirocumab slated to be presented before the end of the year, while the chief competition comes from Amgen with its antibody AMG 145, said Dr Roth. Both antibodies can be delivered via subcutaneous auto-injectors, which many patients say they prefer to taking daily pills, he added.
http://www.pharmatimes.com/Article/13-09-02/Antibody_lipid_treatments_enter_final_furlong.aspx
Alirocumab is a human monoclonal antibody designed for the treatment ofhypercholesterolemia.[1]
This drug was discovered by Regeneron Pharmaceuticals and is being co-developed by Regeron and Sanofi.
THERAPEUTIC CLAIM Treatment of hypercholesterolemia
CHEMICAL NAMES
1. Immunoglobulin G1, anti-(human neural apoptosis-regulated proteinase 1) (human
REGN727 heavy chain), disulfide with human REGN727 κ-chain, dimer
2. Immunoglobulin G1, anti-(human proprotein convertase subtilisin/kexin type 9
(EC=3.4.21.-, neural apoptosis-regulated convertase 1, proprotein convertase 9,
subtilisin/kexin-like protease PC9)); human monoclonal REGN727 des-448-
lysine(CH3-K107)-1 heavy chain (221-220′)-disulfide with human monoclonal
REGN727 light chain dimer (227-227”:230-230”)-bisdisulfide
MOLECULAR FORMULA C6472H9996N1736O2032S42
MOLECULAR WEIGHT 146.0 kDa
SPONSOR Regeneron Pharmaceuticals
CODE DESIGNATION REGN727, SAR236553
CAS REGISTRY NUMBER 1245916-14-6
DCGI asks Wockhardt, Ranbaxy to explain lapses
ALL ABOUT DRUGS BY DR ANTHONY MELVIN CRASTO, WORLD DRUG TRACKER HELPING MILLIONS, MILLION HITS ON GOOGLE……………………………………….
Stick insect leads antibiotic hunt, Norwich researchers say
The gut of the Giant Lime Green stick insect could hold the key to antibiotic resistance
A microbe in the gut of a stick insect could help scientists to unravel the puzzle of antibiotic resistance.
The Giant Lime Green stick insect, which feeds mainly on eucalyptus leaves, is being studied at the John Innes Centre (JIC) in Norwich.
In the laboratory it has shown resistance to toxins and infections it could never have encountered before.
This indicates a general mechanism at work and understanding this could lead to new drugs, JIC scientists believe.
Scientists at JIC are confident studying natural processes will reveal new antibiotics.
The pressure is on to make discoveries because every year more drugs are made ineffective by microbe resistance.
Ants carry antibiotic
Professor Tony Maxwell, head of biological chemistry, said: “We have discovered the microbe in the stick insect’s gut is resistant to toxins and infections…
View original post 390 more words
DRUG APPROVALS BY DR ANTHONY MELVIN CRASTO
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