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ORGANIC SPECTROSCOPY

Read all about Organic Spectroscopy on ORGANIC SPECTROSCOPY INTERNATIONAL 

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DR ANTHONY MELVIN CRASTO Ph.D

DR ANTHONY MELVIN CRASTO Ph.D

DR ANTHONY MELVIN CRASTO, Born in Mumbai in 1964 and graduated from Mumbai University, Completed his Ph.D from ICT, 1991,Matunga, Mumbai, India, in Organic Chemistry, The thesis topic was Synthesis of Novel Pyrethroid Analogues, Currently he is working with AFRICURE PHARMA, ROW2TECH, NIPER-G, Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Govt. of India as ADVISOR, earlier assignment was with GLENMARK LIFE SCIENCES LTD, as CONSUlTANT, Retired from GLENMARK in Jan2022 Research Centre as Principal Scientist, Process Research (bulk actives) at Mahape, Navi Mumbai, India. Total Industry exp 32 plus yrs, Prior to joining Glenmark, he has worked with major multinationals like Hoechst Marion Roussel, now Sanofi, Searle India Ltd, now RPG lifesciences, etc. He has worked with notable scientists like Dr K Nagarajan, Dr Ralph Stapel, Prof S Seshadri, etc, He did custom synthesis for major multinationals in his career like BASF, Novartis, Sanofi, etc., He has worked in Discovery, Natural products, Bulk drugs, Generics, Intermediates, Fine chemicals, Neutraceuticals, GMP, Scaleups, etc, he is now helping millions, has 9 million plus hits on Google on all Organic chemistry websites. His friends call him Open superstar worlddrugtracker. His New Drug Approvals, Green Chemistry International, All about drugs, Eurekamoments, Organic spectroscopy international, etc in organic chemistry are some most read blogs He has hands on experience in initiation and developing novel routes for drug molecules and implementation them on commercial scale over a 32 PLUS year tenure till date Feb 2023, Around 35 plus products in his career. He has good knowledge of IPM, GMP, Regulatory aspects, he has several International patents published worldwide . He has good proficiency in Technology transfer, Spectroscopy, Stereochemistry, Synthesis, Polymorphism etc., He suffered a paralytic stroke/ Acute Transverse mylitis in Dec 2007 and is 90 %Paralysed, He is bound to a wheelchair, this seems to have injected feul in him to help chemists all around the world, he is more active than before and is pushing boundaries, He has 100 million plus hits on Google, 2.5 lakh plus connections on all networking sites, 100 Lakh plus views on dozen plus blogs, 227 countries, 7 continents, He makes himself available to all, contact him on +91 9323115463, email amcrasto@gmail.com, Twitter, @amcrasto , He lives and will die for his family, 90% paralysis cannot kill his soul., Notably he has 38 lakh plus views on New Drug Approvals Blog in 227 countries......https://newdrugapprovals.wordpress.com/ , He appreciates the help he gets from one and all, Friends, Family, Glenmark, Readers, Wellwishers, Doctors, Drug authorities, His Contacts, Physiotherapist, etc He has total of 32 International and Indian awards

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FDA Accepts Endo’s Aveed Application


Endo Health Solutions said that regulators accepted for review new data for its long-acting testosterone injection Aveed and will make a ruling on the drug by Feb. 28. The Food and Drug Administration asked Endo for more information in May.

http://www.dddmag.com/news/2013/09/fda-accepts-endos-aveed-application?et_cid=3463690&et_rid=523035093&type=headline

FULL STORY

Welcome to Bioinfomedical.com


http://www.bioinfomedical.com/index.php

Dr. Rafael B. Boritzer

Prof. Dr. Rafael Boritzer

P.O.Box 88355, Honolulu, Hawaii 96830 U.S.A.

boritzer@bioinfomedical.com

http://www.bioinfomedical.com/index.php

we are marketers of non-branded recombinant proteins with a primary mission of high quality, low priced material for encouraging biopharma research and development outside of North America. We try to integrate our supply services with education of our clients’ with industry videos and information.

Welcome to Bioinfomedical.com

BioInfoMedical was established in 1989 by a team of experienced medical specialists, world-known scientists and marketing professionals. The company has two operating divisions:

InfoMedical Biotechnology and InfoMedical Consulting.

InfoMedical Biotechnology provides products and services used in gene, protein and cell research, drug discovery and development, as well as in biopharmaceutical manufacturing.

InfoMedical Consulting assists companies in strategic market expansion, industry research, environmental analysis, and developing successful market plans for worldwide business-winners.

We are proud to serve our customers around the globe. Our clients are: academic research institutions, biotechnology and pharmaceutical companies, medical research centers, hospitals, reference laboratories, agricultural and chemical companies, as well as leading private and governmental business organizations.

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see a video of DR RAFI

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Cytokines

Growth Factors

Chemokines

CD Antigens

Neurotrophins

Hormones

Enzymes

Viral Antigens

Recombinant Proteins

Natural Proteins

Monoclonal Antibodies

Polyclonal Antibodies

Test Category New

http://www.bioinfomedical.com/index.php

A Return to Health


Unknown's avatarYoga in India

One Woman’s Ayurvedic Experience

by Jodi Boone

Over a cup of tea, she told me how they found her tumour. Mira, a middle-aged woman with large blue eyes and a gentle smile, holds a Ph.D. in Organizational Development and works as an administrator for the Swedish Army.

She explained how the stress and long hours of her work had culminated in 25 kilos of extra weight and high blood pressure. “For 20 years, I didn’t have time for myself – no time for exercise and no energy to shop or cook meals at home,” Mira said. Devoted to her studies in her 20’s and later to her career, Mira acknowledged that her trip to India in 2010 was the first time in her life she’d taken to focus on her health.

“I’d never been to India before, and I’d never heard of Ayurveda,” said Mira. One evening, as she searched…

View original post 955 more words

Fruit Lowers the Risk of Diabetes


Medial Revolt's avatarMedical Revolt

English: Fruit stall in a market in Barcelona,...

The press is all over a recent study done at the Harvard school of public health that was published in the British Medical Journal last week. The study showed that those that ate fruit had a lower risk of diabetes. Specifically they singled out blueberries for a 25% reduction in risk. Grapes offered 11%, apples 5%, prunes 11%, pears 7%. This was not a randomized trial so there are a lot of uncontrolled variables but that being said they did look at 187,382 patients so that sample size does give this study a lot of weight. It also brings further support to a recommendation I have been giving to my diabetic or pre-diabetic patients for years, become a vegan and forget about the ADA (American Diabetes Association) diet.

A study done in 2006 published in Diabetes Care compared patients on a Vegan diet to patients on the ADA diet. The Vegan diet patients…

View original post 311 more words

Theravance Announces FDA Advisory Committee to Review Anoro Ellipta (UMEC/VI) for COPD


The Claimed Intermediate database by Tcipatent Ltd


Eddie Kehoe

Eddie Kehoe

Principal & Technical Director at Tcipatent Ltd

Hove, Brighton and Hove, United KingdomPharmaceuticalsThe Claimed Intermediate – a Structure Searchable Process Patent Database for Marketed Pharmaceutical Drugs (INNs).
Patent examining, searching, analysis and abstracting especially in the Chemical subject area.

http://www.tcipatent.com/

 

          

The Claimed Intermediate is an online database
which covers Process Patents for Named Marketed Pharmaceutical Drugs – whether intermediates are claimed or not – for a low-cost subscription.

  • Structure Searchable
  • Includes INNs in at least one major Market
  • Includes Drug Synthesis often buried in a Plethora of Patents
  • Informs Pipeline decisions
  • Provides targeted Patent data in a Visual form
  • Informs Commercial Synthesis profitability

Click here for more information on our comprehensive solution

http://www.tcipatent.com/

http://www.tcipatent.com/images/tcipatent_sample_report.pdf

shared message from Eddie Kehoe

If anybody would like a trial of the database they could contact either myself eddie.kehoe@tcipatent.com, or my wife and fellow director, Pat Kehoe (pat.kehoe@tcipatent.com).

Here are temporary logons , please request trial

(deactivated automatically in five working days):
Link: Link: www.tcipatent.com/tcidb/
Structure Searchable Patent Database for Processes covering Named Marketed Pharmaceutical Drugs (INNs). The database is an ongoing Watching Service combined with a Backward Drug Service.

Eddie Kehoe
Principal & Technical Director
Tcipatent Ltd
www.tcipatent.com

eddie.kehoe@tcipatent.com

info@tcipatent.om

tcipatent.com
Office: +44 (0)1273 736080
43 Farm Road, Hove, BN3 1FD, United Kingdom

Eddie Kehoe:
eddie.kehoe@tcipatent.com
Mobile – 07425629637
Skype – eddieskihoe

TWITTER-TCIPATENT

Pat Kehoe:
pat.kehoe@tcipatent.com
Mobile – 07585295531
Skype – patkehoe170348

Database Updates:
Recently Added Records

Aliskiren Ambrisentan
Asenapine Atorvastatin
Bosentan Cabazitaxel
Cefamandole Dasatinib
Desogestrel Dexmedetomidine
Docetaxel Doripenem
Doxapram Duloxetine
Etonogestrel Etoricoxib
Etravirine Fluvastatin
Gefitinib Iodixanol
Iohexol Iopamidol
Linagliptin Mitiglinide
Montelukast Moxonidine
Oseltamivir Paclitaxel
Perampanel Pitavastatin
Pravastatin Praziquantel
Ritodrine Rosuvastatin
Silodosin Sitagliptin
Ticagrelor Ulipristal
Zidovudine

………..

photo

Coopers Cask – Pub in Hove BN3 1FB

Eddie is closeby

HOME REMEDIES FOR CHOLESTEROL


Home Remedies for Cholesterol: Onions contain high levels of quercetin, an important flavonoid that reduces cholesterol. high concentrations of the compound quercetin hinderS the oxidation process of LDL, or “bad,” cholesterol, which help prevent the negative effects of this type of cholesterol.

===> http://www.askveda.in/ – Ayurveda health-tips, home remedies & expert advice

Antibody lipid treatments enter final furlong


Antibody lipid treatments enter final furlong

A tiny pain-free jab every two weeks could be the future of cholesterol-lowering for high-risk patients, according to clinical researchers gathered in Amsterdam for the European Society of Cardiology congress.

Eli Roth at the University of Cincinnati said that two companies are currently neck and neck in the race to bring the first PCSK9 antibody to market. Partners Sanofi and Regeneron may have the edge, with Phase III data on their fully human monoclonal antibody alirocumab slated to be presented before the end of the year, while the chief competition comes from Amgen with its antibody AMG 145, said Dr Roth. Both antibodies can be delivered via subcutaneous auto-injectors, which many patients say they prefer to taking daily pills, he added.

http://www.pharmatimes.com/Article/13-09-02/Antibody_lipid_treatments_enter_final_furlong.aspx

Alirocumab is a human monoclonal antibody designed for the treatment ofhypercholesterolemia.[1]

This drug was discovered by Regeneron Pharmaceuticals and is being co-developed by Regeron and Sanofi.

THERAPEUTIC CLAIM Treatment of hypercholesterolemia
CHEMICAL NAMES
1. Immunoglobulin G1, anti-(human neural apoptosis-regulated proteinase 1) (human
REGN727 heavy chain), disulfide with human REGN727 κ-chain, dimer
2. Immunoglobulin G1, anti-(human proprotein convertase subtilisin/kexin type 9
(EC=3.4.21.-, neural apoptosis-regulated convertase 1, proprotein convertase 9,
subtilisin/kexin-like protease PC9)); human monoclonal REGN727 des-448-
lysine(CH3-K107)-1 heavy chain (221-220′)-disulfide with human monoclonal
REGN727  light chain dimer (227-227”:230-230”)-bisdisulfide
MOLECULAR FORMULA C6472H9996N1736O2032S42
MOLECULAR WEIGHT 146.0 kDa

SPONSOR Regeneron Pharmaceuticals
CODE DESIGNATION REGN727, SAR236553
CAS REGISTRY NUMBER 1245916-14-6

  1.  Statement On A Nonproprietary Name Adopted By The USAN Council – Alirocumab,American Medical Association.

DCGI asks Wockhardt, Ranbaxy to explain lapses


ALL ABOUT DRUGS BY DR ANTHONY MELVIN CRASTO, WORLD DRUG TRACKER HELPING MILLIONS, MILLION HITS ON GOOGLE……………………………………….

via DCGI asks Wockhardt, Ranbaxy to explain lapses.

Stick insect leads antibiotic hunt, Norwich researchers say


atasteofcreole's avatarAtasteofcreole's Blog

Giant Lime Green stick insectThe gut of the Giant Lime Green stick insect could hold the key to antibiotic resistance

A microbe in the gut of a stick insect could help scientists to unravel the puzzle of antibiotic resistance.

The Giant Lime Green stick insect, which feeds mainly on eucalyptus leaves, is being studied at the John Innes Centre (JIC) in Norwich.

In the laboratory it has shown resistance to toxins and infections it could never have encountered before.

This indicates a general mechanism at work and understanding this could lead to new drugs, JIC scientists believe.

Scientists at JIC are confident studying natural processes will reveal new antibiotics.

The pressure is on to make discoveries because every year more drugs are made ineffective by microbe resistance.

Ants carry antibiotic

Professor Tony Maxwell, head of biological chemistry, said: “We have discovered the microbe in the stick insect’s gut is resistant to toxins and infections…

View original post 390 more words